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The AB Portable Driver Generates Higher Drive‐Line Pressures Possibly Leading to Accelerated Hemolysis

机译:AB便携式驱动器产生更高的驱动线压力,可能导致加速溶血

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摘要

Abstract The AB5000 Circulatory Support System is paracorporeal pulsatile ventricular assist device. The AB Portable Driver is a portable console for this system. We experienced two cases with accelerated hemolysis while receiving support by the AB Portable Driver. The purpose of this study was to clarify the mechanical differences associated with the hemolysis between the AB5000 console and the AB Portable Driver. The mock circulatory system modeled by an AB5000 ventricle and a blood sampling bag of vinyl chloride was run with an AB5000 console or AB Portable Driver. The peak drive‐line pressure, the mean arterial cannula pressure and the pumping rate of the VAD were recorded. The AB5000 console generated a peak drive‐line pressure of 280–300 mm Hg in LVAD mode and 210–220 mm Hg in RVAD mode, approximately 100 mm Hg lower than officially documented. In contrast, the AB Portable Driver generated pressures of 310–330 mm Hg in LVAD mode and 230–250 mm Hg in RVAD mode, 65–95 mm Hg higher than officially documented. The AB Portable Driver console generates higher drive‐line pressures than the AB5000 console, possibly explaining the accelerated hemolysis.
机译:摘要AB5000循环支撑系统是实体脉冲室心辅助装置。 AB便携式驱动程序是该系统的便携式控制台。我们经历了两种案例,随着AB便携式驱动器接受支持时加速溶血。本研究的目的是阐明与AB5000控制台和AB便携式驱动器之间的溶解相关的机械差异。通过AB5000脑室和氯乙烯的血液采样袋模型的模拟循环系统用AB5000控制台或AB便携式驱动器进行。记录峰值驱动管线压力,平均动脉套管压力和VAD的泵送速率。 AB5000控制台在LVAD模式下产生280-300mm Hg的峰值驱动线压力,在RVAD模式下为210-220 mm Hg,大约100 mm Hg低于正式记录的。相反,AB便携式驱动器在LVAD模式下产生310-330毫米HG的压力,在RVAD模式下为230-250 mm Hg,高于官方记录的65-95 mm Hg。 AB便携式驱动器控制台比AB5000控制台产生更高的驱动线压力,可能解释加速溶血。

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