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首页> 外文期刊>Acta Psychiatrica Scandinavica >Reduced subjective quality of life in persons at risk for psychosis.
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Reduced subjective quality of life in persons at risk for psychosis.

机译:有精神病危险者的主观生活质量下降。

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OBJECTIVE: Subjective quality of life (sQoL) and potentially contributing factors were investigated in individuals putatively in an early (EIPS) or late initial prodromal state (LIPS) and healthy controls (HC). METHOD: Participants comprised 58 EIPS individuals, 157 LIPS individuals and 87 HC individuals. sQoL was assessed together with locus of control (LoC), coping, demography and psychopathology. RESULTS: Putatively prodromal groups exhibited markedly lower sQoL than HC (all domains P < 0.00001). EIPS and LIPS individuals did not differ significantly. Depression was the most consistent explaining variable of sQoL in EIPS and LIPS individuals. In EIPS individuals, LoC emerged as an additional predictor. CONCLUSION: Individuals at risk for psychosis experienced a marked impairment of sQoL across all domains. This was evident even in the early state, showed no significant further deterioration during the late state and was predominantly explained by non-specific symptoms.
机译:目的:对早期(EIPS)或晚期前驱状态(LIPS)和健康对照(HC)的个体进行了主观生活质量(sQoL)和潜在的影响因素调查。方法:参与者包括58名EIPS个人,157名LIPS个人和87名HC个人。评估了sQoL以及控制源(LoC),应对,人口统计学和精神病理学。结果:推定的前驱组的sQoL显着低于HC(所有域P <0.00001)。 EIPS和LIPS个人没有显着差异。抑郁是EIPS和LIPS患者中sQoL的最一致的解释变量。在EIPS个人中,LoC成为其他预测指标。结论:有精神病风险的个体在所有领域都经历了sQoL的明显损害。即使在早期状态下也很明显,在晚期状态下没有显示出进一步的恶化,并且主要由非特异性症状解释。

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