In the Case Report article about a 66-year-old woman with intractable type 1 burning mouth syndrome (BMS), Suda et al. (1) propose the use of a new single therapeutic approach - the electroconvulsive therapy - to the treatment of a patient with persistent symptoms of burning mouth disorder. We congratulate the authors for their efforts focused on BMS therapy. Importantly, we wish to acknowledge the contribution of Suda et al. as the first evidence that the electroconvulsive therapy may have potentially therapeutic implications for patients with BMS. In our view, however, the authors did not consider two important factors that are related to BMS development: acquired nutritional deficiencies and allergic reactions. So, we believe that several aspects of the case report deserve comments. First, type 1 BMS has been reported in patients with B12 deficiency (2, 3); therefore, cobalamin deficiency [B12] is a potential contributing factor that does not appear to have been considered in their report. Second, the BMS may be associated with allergy to dental materials (2, 4-7).
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