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首页> 外文期刊>Australian Forestry >From Chaos to Harmony: Responses and Signaling upon Microbial Pattern Recognition
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From Chaos to Harmony: Responses and Signaling upon Microbial Pattern Recognition

机译:从混乱到和谐:对微生物模式识别时的反应和信号

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摘要

Pathogen- or microbe-associated molecular patterns (PAMPs/MAMPs) are detected as nonself by host pattern recognition receptors (PRRs) and activate pattern-triggered immunity (PTI). Microbial invasions often trigger the production of host-derived endogenous signals referred to as danger-or damage-associated molecular patterns (DAMPs), which are also perceived by PRRs to modulate PTI responses. Collectively, PTI contributes to host defense against infections by a broad range of pathogens. Remarkable progress has been made toward demonstrating the cellular and physiological responses upon pattern recognition, elucidating the molecular, biochemical, and genetic mechanisms of PRR activation, and dissecting the complex signaling networks that orchestrate PTI responses. In this review, we present an update on the current understanding of how plants recognize and respond to nonself patterns, a process from which the seemingly chaotic responses form into a harmonic defense.
机译:通过宿主图案识别受体(PRRS)检测病原体或微生物相关的分子图(PAMPS / MAMPS)作为非本质,并激活模式触发的免疫(PTI)。 微生物侵入通常触发所谓的宿主衍生的内源信号的产生,所述危险或损伤相关的分子模式(潮湿),其也被PRRS调节PTI反应。 总的来说,PTI通过广泛的病原体促进抵抗感染的防御。 已经朝着在模式识别上证明细胞和生理反应的显着进展,阐明了PRR激活的分子,生物化学和遗传机制,并解剖了协调PTI反应的复杂信号网络。 在这篇综述中,我们提出了关于当前了解如何识别和响应不良模式的理解,这是一个看似混乱的反应形成谐波防御的过程。

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