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Measurement of transplanted pancreatic volume using computed tomography: reliability by intra- and inter-observer variability.

机译:使用计算机断层摄影术测量移植的胰腺体积:观察者间和观察者间变异性的可靠性。

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Background Unlike other solid organ transplants, pancreas allografts can undergo a substantial decrease in baseline volume after transplantation. This phenomenon has not been well characterized, as there are insufficient data on reliable and reproducible volume assessments. We hypothesized that characterization of pancreatic volume by means of computed tomography (CT) could be a useful method for clinical follow-up in pancreas transplant patients. Purpose To evaluate the feasibility and reliability of pancreatic volume assessment using CT scan in transplanted patients. Material and Methods CT examinations were performed on 21 consecutive patients undergoing pancreas transplantation. Volume measurements were carried out by two observers tracing the pancreatic contours in all slices. The observers performed the measurements twice for each patient. Differences in volume measurement were used to evaluate intra- and inter-observer variability. Results The intra-observer variability for the pancreatic volume measurements of Observers 1 and 2 was found to be in almost perfect agreement, with an intraclass correlation coefficient (ICC) of 0.90 (0.77-0.96) and 0.99 (0.98-1.0), respectively. Regarding inter-observer validity, the ICCs for the first and second measurements were 0.90 (range, 0.77-0.96) and 0.95 (range, 0.85-0.98), respectively. Conclusion CT volumetry is a reliable and reproducible method for measurement of transplanted pancreatic volume.
机译:背景技术与其他实体器官移植不同,胰腺同种异体移植可在移植后的基线体积上大幅减少。由于缺乏可靠和可重复的体积评估的数据,因此尚未很好地表征这种现象。我们假设通过计算机断层扫描(CT)表征胰腺体积可能是对胰腺移植患者进行临床随访的有用方法。目的通过CT扫描评估移植患者胰脏体积评估的可行性和可靠性。材料和方法对21例接受胰腺移植的患者进行CT检查。由两名观察员在所有切片中追踪胰腺轮廓进行体积测量。观察者对每个患者进行两次测量。体积测量的差异用于评估观察者之间和观察者之间的变异性。结果发现观察者1和观察者2的胰脏体积测量值的观察者内部变异性几乎完美一致,组内相关系数(ICC)分别为0.90(0.77-0.96)和0.99(0.98-1.0)。关于观察者之间的有效性,第一次和第二次测量的ICC分别为0.90(范围0.77-0.96)和0.95(范围0.85-0.98)。结论CT容积法是一种可靠且可重复的方法,可用于测量移植的胰腺体积。

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