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首页> 外文期刊>Acta Radiologica >Breast leukemia: An update
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Breast leukemia: An update

机译：乳腺癌：最新情况

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Background: Breast leukemia is extremely rare. The published data on this manifestation include predominantly case reports and do not provide any statistical information. Purpose: To identify clinical signs and radiological features of breast leukemia. Material and Methods: PubMed and Medline databases between 1980 and 2010 were screened using 'breast leukemia' and 'leukemia of the breast' as keywords. Secondary references were also reviewed. By this search, a total of 139 patients were identified from the literature. Results: In most patients (n = 85, 61.2%) acute myeloid leukemia was diagnosed. Acute lymphatic leukemia occurred in 35 patients (25.2%). Isolated BL before bone marrow infiltration was seen in 24 patients (17.3%). Involvement of the breast during the course of leukemia was diagnosed in 25 cases (18%). Intramammary leukemic relapse after therapy/stem cell transplantation occurred in 59 patients (42.4%). In 71 cases (51.1%) the lesions were solitary and in 57 (41%) multiple. The number of lesions was not reported in 11 patients (7.9%). There was no significant difference between the number of lesions in ML and LL. Clinically, 73% of the patients presented with palpable breast masses. Most of them were painless. Mammography was performed in 39 patients, allowing the identification of the following three mammographic patterns: breast masses (28 patients, 72%), architectural distortion (5 patients, 13%), no abnormalities (6 patients, 15%). On ultrasound, most identified masses were homogeneously hypoechoic with microlobulated or indistinct margins. On MRI, on T2-weighted images breast lesions were hyperintense. After venous administration of contrast medium, BL showed marked inhomogeneous contrast enhancement. Treatment of BL is the same as for other localizations and is based on chemotherapy and/or radiotherapy. Conclusion: In the present study the clinical and radiological features of BL are described. They are non-specific. However, BL should be considered in the differential diagnosis of breast disorders, especially in patients with leukemia.
机译：背景：乳腺癌是极为罕见的。有关此表现形式的已发布数据主要包括病例报告，并且不提供任何统计信息。目的：确定乳腺癌的临床体征和影像学特征。资料和方法：使用“乳腺癌”和“乳腺癌”作为关键词，筛选1980年至2010年之间的PubMed和Medline数据库。二级参考文献也进行了审查。通过该搜索，从文献中总共鉴定出139名患者。结果：大多数患者（n = 85，61.2％）被诊断出急性髓细胞性白血病。急性淋巴白血病发生在35例患者中（25.2％）。在24名患者中观察到了骨髓浸润前的孤立BL（17.3％）。在25例（18％）的病例中，诊断出白血病累及乳房。治疗/干细胞移植后乳房内白血病复发发生在59例患者中（42.4％）。在71例（51.1％）的病变中，病变是孤立的，在57例（41％）的病变中。 11例患者（7.9％）未报告病变数目。 ML和LL的病变数目之间没有显着差异。临床上，有73％的患者出现明显的乳房肿块。他们大多数人都很无痛。在39例患者中进行了乳房X线摄影，可以识别以下三种乳房X线照片：乳房肿块（28例，72％），结构畸变（5例，13％），无异常（6例，15％）。在超声检查中，大多数鉴别出的肿块均呈低回声，边缘呈微叶状或模糊不清。在MRI上，在T2加权图像上，乳腺病变是高强度的。静脉注射造影剂后，BL显示出明显的不均匀的造影剂增强。 BL的治疗与其他位置相同，并且基于化学疗法和/或放射疗法。结论：本研究描述了BL的临床和放射学特征。它们是非特定的。但是，在乳腺疾病的鉴别诊断中应考虑BL，尤其是在白血病患者中。

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