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首页> 外文期刊>Acta Radiologica >Changes in brain FDG metabolism induced by acupuncture in healthy volunteers.
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Changes in brain FDG metabolism induced by acupuncture in healthy volunteers.

机译：健康志愿者通过针灸诱发的大脑FDG代谢变化。

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BACKGROUND: With the aid of newly developed functional brain imaging studies, studies are ongoing to see if acupuncture first acts on specific brain areas to induce effects on the human body. PURPOSE: To examine if stimulation at specific acupuncture points changes brain glucose metabolism patterns, including the limbic system and specific brain areas related to the acupuncture effect in healthy volunteers using fluorodeoxyglucose positron emission tomography combined computed tomography (FDG-PET/CT). MATERIAL AND METHODS: Twenty healthy volunteers (11 men and 9 women; mean age 49.1+/-7.3 years, age range 35-62 years) were included. Two sets of PET/CT scans were obtained from each volunteer, with and without stimulation by acupuncture. Two classic acupoints, LR3 (liver meridian) and ST44 (stomach meridian) were tested at the same time, using disposable sterile stainless steel needles. After initial acupuncture, the needle was kept in place without further stimulation. FDG-PET/CT scan of the brain began 45 min after FDG injection (185-222 MBq). RESULTS: After stimulation of LR3 and ST44 by acupuncture, glucose metabolism in the brain was increased in the left insula (BA 13), bilateral thalami, superior frontal region of the right frontal lobe, and the inferior frontal region of left frontal lobe compared with baseline. On the other hand, glucose metabolism was decreased after acupuncture in the cingulate and parahippocampal (BA 36) regions of the left limbic lobe. CONCLUSION: Changes of glucose metabolism in specific brain areas following stimulation by acupuncture on LR3 and ST44 were documented using FDG-PET/CT.
机译：背景：借助新近开发的功能性脑成像研究，正在进行研究，以了解针灸是否首先作用于特定的大脑区域以对人体产生影响。目的：使用氟脱氧葡萄糖正电子发射断层扫描结合计算机断层扫描（FDG-PET / CT），检查在健康的志愿者中，特定针刺点的刺激是否改变了脑葡萄糖代谢模式，包括边缘系统和与针刺效应相关的特定脑区域。材料与方法：纳入20名健康志愿者（11名男性和9名女性;平均年龄49.1 +/- 7.3岁，年龄范围35-62岁）。从每位志愿者获得两组PET / CT扫描，无论有无针刺刺激。使用一次性无菌不锈钢针头同时测试了两个经典穴位LR3（肝脏子午线）和ST44（胃子午线）。初次针刺后，将针头固定在原位，无需进一步刺激。注射FDG（185-222 MBq）后45分钟开始对大脑进行FDG-PET / CT扫描。结果：针刺刺激LR3和ST44后，左岛（BA 13），双侧丘脑，右额叶上额叶区域和左额叶下额叶区域的脑内葡萄糖代谢均高于对照组。基线。另一方面，针刺后左缘叶的扣带和海马旁（BA 36）区域，葡萄糖代谢下降。结论：FDG-PET / CT记录了针刺LR3和ST44刺激后特定脑区葡萄糖代谢的变化。

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