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首页> 外文期刊>Acta Radiologica >Imaging features of idiopathic intracranial hypertension, including a new finding: Widening of the foramen ovale
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Imaging features of idiopathic intracranial hypertension, including a new finding: Widening of the foramen ovale

机译：特发性颅内高压的影像学特征，包括一个新发现：卵圆孔扩大

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Background: Idiopathic intracranial hypertension (IIH) is a clinical disorder of unknown etiology manifesting with increased intracranial pressure in the absence of hydrocephalus, an underlying mass lesion, and demonstrating normal cerebrospinal fluid composition. IIH may exhibit several non-specific imaging findings including: an empty sella, posterior globe flattening, tortuosity of the optic nerve, and optic nerve sheath distention. Purpose: To introduce widening of the foramen ovale as a new imaging marker for IIH. Material and Methods: IIH is a syndrome which may exhibit several previously described non-specific imaging findings including: an empty sella, posterior globe flattening, tortuosity of the optic nerve, and optic nerve sheath distention. We hypothesize that chronically elevated cerebrospinal fluid pressure can lead to osseous erosions and we propose widening of the foramen ovale as a new imaging marker for IIH. Results: Average foramen ovale sizes were increased in patients with IIH compared to controls (30.03± 7.00 mm 2 vs. 24.21±5.97 mm 2, P, 0.001). For a cut-off value of 30 mm 2, the sensitivity of FO area to detect IIH was 50%, with 81% specificity. Classic findings were significantly more common in patients with IIH compared to controls including: empty sella (65.9% vs. 0%), posterior globe flattening (65.9% vs. 4.5%), vertical tortuosity of the optic nerve (54.5% vs. 9.1%), and optic nerve sheath distention (52.3% vs. 11.4%, all P values 0.001). Conclusion: Our study confirms the association of several classic imaging findings with IIH and supports widening of the foramen ovale as an additional imaging marker which may be incorporated into the evaluation of patients suspected to have this condition.
机译：背景：特发性颅内高压症（IIH）是一种病因不明的临床疾病，表现为在没有脑积水，潜在的肿块病变以及脑脊液成分正常的情况下颅内压升高。 IIH可能表现出一些非特异性的影像学表现，包括：空蝶鞍，后球变平，视神经弯曲和视神经鞘管扩张。目的：引入加宽卵圆孔作为IIH的新影像学标记。材料和方法：IIH是一种综合症，可能表现出一些先前描述的非特异性影像学表现，包括：空蝶鞍，后球变平，视神经弯曲和视神经鞘管扩张。我们假设慢性脑脊髓液压力升高会导致骨侵蚀，我们建议扩大卵圆孔作为IIH的新影像学标记。结果：与对照组相比，IIH患者的平均卵圆孔尺寸增加了（30.03±7.00 mm 2与24.21±5.97 mm 2，P，0.001）。对于30 mm 2的临界值，FO区域检测IIH的灵敏度为50％，特异性为81％。与对照组相比，IIH患者的经典发现更为常见，包括：空蝶鞍（65.9％vs. 0％），后球变平（65.9％vs. 4.5％），视神经垂直弯曲（54.5％vs. 9.1）。 ％）和视神经鞘管扩张（52.3％比11.4％，所有P值<0.001）。结论：我们的研究证实了几种经典影像学发现与IIH的关联，并支持扩大卵圆孔作为额外的影像学标记，可将其纳入怀疑患有此病的患者的评估中。

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