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首页> 外文期刊>Acta Radiologica >64 multidetector CT findings of influenza A (H1N1) virus in patients with hematologic malignancies
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64 multidetector CT findings of influenza A (H1N1) virus in patients with hematologic malignancies

机译：血液系统恶性肿瘤患者中64例A型H1N1流感病毒的多探测器CT表现

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Background: The pandemic of swine-origin H1N1 influenza that began in early 2009 has provided evidence that radiology can assist in the early diagnosis of severe cases. Immunocompromised patients are at increased risk for morbidity and mortality. MDCT is superior to radiography in showing the distribution of the disease. Purpose: To review the 64 multidetector CT thoracic findings of novel swine-origin influenza A (H1N1) virus in patients with hematologic malignancies. Material and Methods: This study included 12 patients (3 women, 9 men; mean age, 32.2 years). All patients proved to be infected with influenza A (H1N1) virus. The hematologic malignancies were acute myeloid leukemia (n = 8), chronic lymphocytic leukemia (n = 2), multiple myeloma (n = 1), and myelodysplastic syndrome (n = 1). All the patients underwent CT scanning using a 64 multidetector CT scanner. Chest CT scans were reviewed for ground-glass opacities (GGOs), consolidation, airway thickening/dilatation, nodules, mediastinal lymphadenopathy, and pleural effusion. Results: More than one CT finding was detected in every patient. Pulmonary affection was bilateral, more on the left side. The affections were mainly peribronchial. Airway wall thickening and dilatation were detected in all 12 patients, GGO in 9/12 patients, nodules in 6/12 patients, consolidation in 6/12 patients, hilar lymphadenopathy in 3/12 patients, and pleural effusion in 2/12 patients. Conclusion: Acute myeloid leukemia is the most common hematologic malignancy affected by influenza A (H1N1) virus. The left lung is affected more than the right one. The most common multidetector CT findings are unilateral or bilateral airway thickening and dilatation. Multidetector CT can be used for early and accurate assessment of pulmonary affection with influenza A H1N1 virus infection.
机译：背景：2009年初开始的猪源性H1N1流感大流行提供了证据，表明放射学可以帮助早期诊断严重病例。免疫功能低下的患者发病和死亡的风险增加。 MDCT在显示疾病分布方面优于放射线照相。目的：回顾血液恶性肿瘤患者中新型猪源性甲型H1N1流感病毒的64台多探测器CT胸部发现。材料和方法：这项研究包括12例患者（3名女性，9名男性;平均年龄32.2岁）。所有患者均被证明感染了甲型H1N1流感病毒。血液系统恶性肿瘤为急性髓细胞性白血病（n = 8），慢性淋巴细胞性白血病（n = 2），多发性骨髓瘤（n = 1）和骨髓增生异常综合症（n = 1）。所有患者均使用64位多探测器CT扫描仪进行了CT扫描。回顾了胸部CT扫描是否存在玻璃液混浊（GGO），结实，气道增厚/扩张，结节，纵隔淋巴结肿大和胸腔积液。结果：每位患者均发现了一个以上的CT发现。肺部感染是双侧的，更多在左侧。情感主要是支气管周围。在所有12例患者中检测到气道壁增厚和扩张，在9/12例中发现GGO，在6/12例中发现结节，在6/12例中出现结节，在3/12例中发现肺门淋巴结病，在2/12例中发现胸腔积液。结论：急性髓细胞性白血病是受甲型H1N1病毒感染的最常见的血液系统恶性肿瘤。左肺受累的程度要多于右肺。多探测器CT最常见的发现是单侧或双侧气道增厚和扩张。 Multidetector CT可用于A流感H1N1病毒感染的早期和准确评估肺部感染。

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