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首页> 外文期刊>Indian journal of physiology and pharmacology >iodine in Excess: Impact on Ovarian and Uterine Histology in Adult Rats
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iodine in Excess: Impact on Ovarian and Uterine Histology in Adult Rats

机译：过度碘：对成年大鼠卵巢和子宫组织学的影响

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摘要

Iodine is a key component of thyroid hormones. Iodine deficiency as well as iodine excess causes thyroid disorders. Universal salt iodization has led to exposure to iodine above the recommended levels in environmentally iodine sufficient regions disrupting thyroid physiology and in turn affecting reproductive physiology. Effects of excess iodine on male reproductive organ is well studied but studies on ovarian and uterine structural changes are scanty. Hence the present study investigates the histological changes in the ovary and uterus after prolonged exposure to iodine in excess. The study clearly indicates changes in ovarian follicular and corpus luteum number and structure. This was also accompanied by altered luminal structure and number of secretory glands in the uterus. The probable cause was ovarian iodine accumulation and altered thyroid physiology. Thus prolonged exposure of iodine in excess altered the normal histological structure of ovary and uterus, posing detrimental to female reproductive system.
机译：碘是甲状腺激素的关键组成部分。碘缺乏和碘过量导致甲状腺疾病。通用盐碘化导致在受环境碘量足够区域的推荐水平上方接触碘，破坏甲状腺生理，然后影响生殖生理学。过量碘对雄性生殖器官的影响很好地研究，但研究卵巢和子宫结构变化很少。因此，本研究研究了延长暴露于过量的碘后卵巢和子宫的组织学变化。该研究清楚地表明卵巢卵泡和语料卵黄数和结构的变化。这也伴随着子宫内的腔腔结构和分泌腺数量。可能的原因是卵巢碘积累和改变的甲状腺生理学。因此，碘的延长曝光过度改变了卵巢和子宫的正常组织学结构，造成对雌性生殖系统的不利影响。

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