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首页> 外文期刊>Indian medical journal >Epidural Analgesia with Fentanyl and Bupivacaine Provides Better Analgesia than Intravenous Morphine Patient-Controlled Analgesia for Early Thoracotomy Pain
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Epidural Analgesia with Fentanyl and Bupivacaine Provides Better Analgesia than Intravenous Morphine Patient-Controlled Analgesia for Early Thoracotomy Pain

机译：与芬太尼和布比卡因的硬膜外镇痛提供比静脉内吗啡患者控制镇痛的更好的镇痛，用于早期胸廓疼痛

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Intravenous patient-controlled analgesia (IVPCA) and patient-controlled epidural analgesia (PCEA) were studied in terms of analgesic efficacy, respiratory function and side effects after thoracic surgery for 24h. PCEA using fentanyl and bupivacaine as compared to IVPCA using morphine provides better pain relief both at rest and during coughing and is associated with fewer side effects. Thirty ASA-1 or II patients undergoing thoracotomy were assigned randomly to. receive either IVPCA using morphine or PCEA using fentanyl and bupivacaine combination postoperatively. No background infusion was administered in either group. Postoperative evaluation included pain intensity both at rest and during coughing, degree of sedation, arterial blood gas, forced vital capacity (FVC), peak expiratory flow rate (PEFR), presence of side effects such as nausea/vomiting and pruritis at 0, 2,8, 12 and 24h. The primary outcome of the study was the percentage of patients with analgesia failure defined as VASxJO despite three consecutive PCA boluses requiring rescue .analgesia with intravenous fentanyl. Patients in the PCEA group were less sedated and had fewer incidences of side effects, i.e. nausea/vomiting and pruritis. After thoracic surgery, PCEA using fentanyl and bupivacaine as compared to IVPCA using morphine provides better pain relief both at rest and during coughing and associated with fewer side effects.
机译：在镇痛疗效，胸腔手术后患者疗效，呼吸功能和副作用，研究了静脉注射患者控制的镇痛（IVPCA）和患者控制的硬膜外镇痛（PCEA）。 PCEA使用Fentanyl和Bupivacaine与使用吗啡的IVPCA相比，在休息和咳嗽期间，既休息和咳嗽也会提供更好的疼痛缓解，并且与较少的副作用有关。经过三十asa-1或II患者随机分配到接受胸廓切开术的患者。术后使用芬太尼和Bupivacaine组合使用吗啡或PCEA接收IVPCA。在任一组中没有施用背景输注。术后评价包括静止和咳嗽期间的疼痛强度，镇静程度，动脉血气，强制急性容量（FVC），峰值呼气流速（PEFR），副作用的存在，如恶心/呕吐和瘙痒率为0，2 ，8,12和24h。该研究的主要结果是镇痛失败的患者定义为Vasxjo的百分比，尽管有三个连续的PCA Zoluses需要抢救。具有静脉注射芬太尼的血糖。 PCEA组的患者较少镇静，副作用较少，即恶心/呕吐和瘙痒症。在胸外科术后，使用芬太尼和Bupivacaine使用吗啡使用芬太尼群，在休息和咳嗽期间，既咳嗽也会提供更好的疼痛缓解，与较少的副作用相关。

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