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Perceived versus proven SARS-CoV-2-specific immune responses in health-care professionals

机译:在医疗保健专业人员中感知与验证SARS-COV-2特异性免疫反应

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摘要

There have been concerns about high rates of thus far undiagnosed SARS-CoV-2 infections in the health-care system. The COVID-19 Contact (CoCo) Study follows 217 frontline health-care professionals at a university hospital with weekly SARS-CoV-2-specific serology (IgA/IgG). Study participants estimated their personal likelihood of having had a SARS-CoV-2 infection with a mean of 21% [median 15%, interquartile range (IQR) 5-30%]. In contrast, anti-SARS-CoV-2 IgG prevalence was about 1-2% at baseline. Regular anti-SARS-CoV-2 IgG testing of health-care professionals may aid in directing resources for protective measures and care of COVID-19 patients in the long run.
机译:涉及到迄今为止未确诊的SARS-COV-2在保健系统中感染的高率。 Covid-19联系人(Coco)学习在大学医院的217名前线医疗专业人员,每周317名患有每周SARS-COV-2特异性血清学(IGA / IGG)。 研究参与者估计他们具有SARS-COV-2感染的个人可能性,平均值为21%[中位数15%,间条款范围(IQR)5-30%]。 相比之下,抗SARS-COV-2 IgG患病率在基线下为约1-2%。 经常抗SARS-COV-2 IGG检测卫生保健专业人员可能有助于从长远来看指导资源保护措施和Covid-19患者的护理。

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