首页> 外文期刊>Acta Radiologica >Cortical restricted diffusion as the predominant MRI finding in sporadic Creutzfeldt-Jakob disease.
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Cortical restricted diffusion as the predominant MRI finding in sporadic Creutzfeldt-Jakob disease.

机译:皮质限制扩散是散发性Creutzfeldt-Jakob病的主要MRI发现。

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摘要

Creutzfeldt-Jakob disease is a rare and fatal neurodegenerative disorder with MR findings predominantly limited to the grey matter of the cortex and the basal ganglia. Sporadic Creutzfeldt-Jakob disease can produce a spectrum of MR imaging findings of the brain, most notably on DWI and FLAIR sequences. Involvement of the basal ganglia and neocortex is the most common finding, but isolated involvement of the cortex can also be seen. We describe the clinical history and MRI findings of three patients with sporadic Creutzfeldt-Jakob disease confirmed by brain biopsy or autopsy and review the literature of imaging manifestations of this disease.
机译:Creutzfeldt-Jakob病是一种罕见的致命性神经退行性疾病,其MR发现主要限于皮质和基底神经节的灰质。偶发性Creutzfeldt-Jakob病会产生一系列的MR影像学表现,尤其是在DWI和FLAIR序列上。基底神经节和新皮层受累是最常见的发现,但也可看到皮层受累。我们描述了通过脑活检或尸检证实的三例散发性Creutzfeldt-Jakob病患者的临床病史和MRI表现,并回顾了该病的影像学表现。

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