...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BJU international >Positron emission tomography with 18fluorine-labelled deoxyglucose: utility in localized and advanced prostate cancer.
【24h】

Positron emission tomography with 18fluorine-labelled deoxyglucose: utility in localized and advanced prostate cancer.

机译：用18氟标记的脱氧葡萄糖进行正电子发射断层扫描：在局部和晚期前列腺癌中的效用。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE: To determine the role of the positron emission tomography (PET) with 18F-labelled deoxyglucose in the identification of prostatic cancer in the iliac and obturator lymphatic nodes before radical prostatectomy, and in the localization of relapse in patients in biochemical progression. PATIENTS AND METHODS: Twenty-one patients were divided into two groups. Group A consisted of 11 men diagnosed with organ-confined prostate cancer, where attention was focused on the iliac and obturator lymphatic nodes, the results being compared with the pathological anatomy obtained from surgical procedures. Group B included 10 patients treated by radical prostatectomy, radiotherapy or orchidectomy and who were in biochemical progression, in whom the aim was to identify recurrence of the disease. RESULTS: In none of the 11 patients of group A who had undergone radical prostatectomy were deposits of radiotracer identified in the area of the iliac and obturator nodes which would indicate node metastases. However, the histopathological analysis of these nodes showed tumour in three patients. In group B the PET scans showed recurrence of prostate cancer (by deposits of radiotracer) more clearly than did computed tomography (CT) in two patients (both with recurrence in soft tissue). In one patient bone scintigraphy identified a lesion compatible with prostatic disease in the bone; this was clinically confirmed but was not identified by PET. CONCLUSION: PET, using deoxyglucose labelled with 18F, cannot reliably identify prostatic adenocarcinoma in the iliac and obturator lymph nodes before surgery; other tracers may give better results. To locate relapses in patients with biochemical progression, PET seems to have better sensitivity than CT when identifying diseases in soft tissues and is possibly inferior to bone scintigraphy in detecting bony metastases.
机译：目的：确定18F标记的脱氧葡萄糖正电子发射断层扫描（PET）在前列腺癌根治性切除术之前在and和闭孔淋巴结的前列腺癌鉴定中以及在生化进程中确定患者复发位置中的作用。患者与方法：21例患者分为两组。 A组由11位被诊断患有器官受限前列腺癌的男性组成，他们的注意力集中在ilia和闭孔淋巴结上，并将结果与​​手术方法获得的病理解剖学进行了比较。 B组包括10例接受前列腺癌根治术，放射疗法或睾丸切除术治疗且处于生化进程的患者，其目的是确定疾病的复发。结果：A组的11例行根治性前列腺切除术的患者中，没有一例发现放射性示踪剂沉积在and和闭孔结区域，这表明有结节转移。然而，对这些淋巴结的组织病理学分析显示三名患者患有肿瘤。在B组中，PET扫描显示前列腺癌的复发（通过放射性示踪剂的沉积）比计算机断层扫描（CT）的两名患者（均在软组织中复发）更清晰。在一名患者的骨闪烁显像仪中发现了与骨中前列腺疾病相适应的病变。这在临床上已得到证实，但PET并未确定。结论：PET使用18F标记的脱氧葡萄糖不能可靠地识别before和闭孔淋巴结中的前列腺腺癌。其他示踪剂可能会提供更好的结果。为了确定生化进展患者的复发情况，PET在鉴别软组织疾病时的敏感性似乎比CT更好，并且在检测骨转移方面可能不如骨闪烁显像。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号