...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Epidemiology: Official Journal of the International Epidemiological Association >The nature of behavioural correlates of healthy ageing: A twin study of lifestyle in mid to late life
【24h】

The nature of behavioural correlates of healthy ageing: A twin study of lifestyle in mid to late life

机译：健康老龄化行为关联的性质：中到晚期生活方式的双胞胎研究

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: With the greying of the industrialized world has come increased interest in identifying the modifiable lifestyle factors that promote healthy and successful ageing. Whereas many of the behavioural correlates of late-life morbidity and mortality have been identified, relatively little is known about the origins of individual differences in these factors.Methods: A sample of 12 714 twins, including both members of 3806 pairs of known zygosity, ascertained through the Danish Twin Registry and aged 40 to 80 years, completed a self-report assessment of six lifestyle factors associated with ageing: smoking, drinking, diet and physical, social and intellectual activities. Standard biometric methods were used to analyse the twin data and determine the extent to which individual differences in each of the lifestyle factors are heritable.Results: For each of the six lifestyle factors, the estimate of heritability ranged from 32% (95% CI: 19-42%) for the diet scale to 69% (62-72%) for the smoking measure. Biometric estimates of the contribution of the twins' common rearing environment were uniformly small (≤6%). There was little evidence that standardized biometric estimates varied by gender or age.Conclusions: Individuals likely construct lifestyles in part to complement and reinforce underlying genetically influenced dispositions and talents. The heritable nature of lifestyle factors implies that the behavioural and genetic contributors to ageing processes are not necessarily conceptually distinct but rather reflect the complexity of gene-environment interplay in ageing.
机译：背景：随着工业化世界的灰色，对确定可修改的生活方式因素来增加促进健康和成功的衰老的兴趣。然而，许多行为相关性发病率和死亡率的相关性相关，而是对这些因素中的个体差异的起源是相对较少的。方法：12 714孪胞胎的样品，包括3806对已知的Zygosity的两个成员，通过丹麦双人登记处和40岁至80年来确定，完成了与老龄化相关的六种生活方式因素的自我报告评估：吸烟，饮酒，饮食和物理，智力活动。标准生物识别方法用于分析双数据，并确定每个生活方式因素中各个差异的程度是可遗传的。结果：对于六种生活方式因素中的每一个，遗传性的估计率范围为32％（95％CI： 19-42％）为吸烟措施的饮食规模为69％（62-72％）。双胞胎普通饲养环境的贡献的生物识别估计均匀小（≤6％）。几乎没有证据表明，性别或年龄的标准化生物识别估计变化.Conclusions：个人可能构建生活方式，部分化以补充和加强基因影响的性格和人才。生活方式因素的遗传性质意味着对老化过程的行为和遗传贡献者不一定是概念上的，而是反映了基因环境的复杂性在老化中的相互作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号