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首页> 外文期刊>International journal of immunogenetics >Distribution of ABO and RHD blood group antigens in blood donors in Burkina Faso
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Distribution of ABO and RHD blood group antigens in blood donors in Burkina Faso

机译：布基纳法索献血者中ABO和RHD血型抗原的分布

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摘要

Geographical distribution of ABO and RHD antigens is important for blood transfusion services and population genetics studies. There are few data on this topic in Burkina Faso, a multi-ethnic country. Our study aims at reporting phenotypic and allelic frequencies of ABO and RHD blood groups among voluntary blood donors from various ethnical regions of Burkina Faso. We conducted a cross-sectional study including 81,486 blood donors. ABO allelic frequencies were determined using the Bernstein method. Differences in phenotypic distribution of blood groups were assessed using the chi-square test; a p value B+A+AB+O-B-A-AB- in our population. Phenotypic frequencies of blood groups A, B, O and AB were respectively 22.54%, 28.56%, 43.30% and 5.60%. RHD+was 92.24%. The allelic frequencies of A, B, O and D were respectively 0.1524; 0.1887; 0.6590 and 0.7214. We noticed statistical differences (p 0.05) between these administrative regions which corresponded roughly to some natural ethnic areas. Indeed, the phenotype O was more frequent in the Central-west, Central and East regions corresponding to "Mossi," "Gourounsi," "Gourmantche" areas while the phenotype A and AB were more reported in "Boucle du mouhoun" and "Hauts-Bassins" regions where we have "Bwaba" and "Bobo." The phenotype O negative was less frequent in "Bwaba." Our study provides interesting information to blood services that will allow them to better refine their donor recruitment strategies.
机译：ABO和RHD抗原的地理分布对于输血服务和人口遗传学研究很重要。 Burkina Faso的数据很少有一个多民族国家。我们的研究旨在报告来自Burkina Faso的各种州地区的自愿献血者中ABO和RHD血液的表型和等位基因频率。我们进行了一个横断面研究，包括81,486名献血者。使用Bernstein方法测定ABO等位基因频率。使用Chi-Square测试评估血型表型分布的差异; P值B +＆ a +＆ ab +＆ o-＆ b-＆ a-＆在我们的人口中。血液组A，B，O和AB的表型频率分别为22.54％，28.56％，43.30％和5.60％。 RHD +为92.24％。 A，B，O和D的等位基因频率分别为0.1524; 0.1887; 0.6590和0.7214。我们注意到这些行政区域之间的统计学差异（P <0.05），这些行政区域大致与某些自然民族区域相对应。实际上，在与“苔藓”的中央和东部地区相对应频繁的表型O更频繁，“Gourounsi”的“Gourousche”区域，而在“Boucle du Mouhoun”和“Hauts”中更符合表型A和AB -Bassins“我们有”Bwaba“和”Bobo“的地区。在“Bwaba”中，阴性的表型甚至不太频繁。我们的研究为血液服务提供了有趣的信息，使他们能够更好地改善捐助者招聘策略。

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