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首页> 外文期刊>International journal of molecular imaging >Accuracy of Hepatobiliary Scintigraphy after Liver Transplantation and Liver Resection
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Accuracy of Hepatobiliary Scintigraphy after Liver Transplantation and Liver Resection

机译：肝移植和肝切除术后肝胆闪烁术的准确性

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Background and Aims. Biliary complications are the most frequent complications after common liver surgeries. In this study, accuracy of hepatobiliary scintigraphy (HBS) and impact of hyperbilirubinemia were evaluated. Methods. Between November 2007 and February 2016,131 patients underwent hepatobiliary scintigraphy after having liver surgery. 39 patients with 42 scans after LTX (n = 13) or hepatic resection (n = 26) were evaluated in the study; 27 were male, with mean age 60 years. The subjects underwent hepatobiliary scintigraphy with Tc-99m labeled Mebrofenin. The results were compared to ERCP as gold standard performed within one month after HBS. We calculated sensitivity, specificity, PPV, and NPV. We compared LTX patients to patients with other liver surgeries. Furthermore the influence of hyperbilirubinemia on HBS scans was evaluated. Results. HBS always provided the correct diagnosis in cases of bile leak in the liver-resected group (14/14). Overall diagnostic accuracy was 76% (19/25) in this group and 54% (7/13) in the LTX group. False negative (FN) diagnoses occurred more often among LTX patients (p = 0.011). Hyperbilirubinemia (>5 mg/dL) significantly influenced the excretion function of the liver, prolonging HBS's time-activity-curve (p = 0.001). Conclusions. Hepatobiliary scintigraphy is a reliable tool to detect biliary complications, but reduced accuracy must be considered after LTX.
机译：背景和目标。胆道并发症是常见肝脏手术后最​​常见的并发症。在这项研究中，评估了肝胆闪烁扫描（HBS）的准确性和血红蛋白血症的影响。方法。 2007年11月至2016,131患者在肝脏手术后接受了肝胆闪烁扫描的患者。在研究中，在LTX（n = 13）或肝切除（n = 26）后，39例扫描患者在研究中进行了评估; 27是男性，平均年龄为60岁。受试者接受肝胆闪烁扫描，TC-99M标记的Mebrofenin。将结果与ERCP进行比较，因为HBS后一个月内进行的金标准。我们计算敏感性，特异性，PPV和NPV。我们将LTX患者与其他肝脏手术进行比较。此外，评估了Hyperbilirubinemia对HBS扫描的影响。结果。 HBS始终为肝切除组（14/14）的胆汁泄漏的情况下提供了正确的诊断。整体诊断准确率为该组76％（19/25），LTX组中为54％（7/13）。在LTX患者中较常见的假阴性（FN）诊断（P = 0.011）。高胆管素血症（> 5mg / dl）显着影响肝脏的排泄功能，延长HBS的时间活性曲线（P = 0.001）。结论。肝胆道闪烁扫描是一种可靠的工具来检测胆道并发症，但在LTX后必须考虑降低的精度。

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