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Thermo-expandable intraprostatic stents in bladder outlet obstruction: an 8-year study.

机译:膀胱出口梗阻热膨胀前列腺内支架:一项为期8年的研究。

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摘要

Objective To assess the use of a thermo-expandable intraprostatic stent (Memokath(R), Engineers and Doctors A/S, Copenhagen, Denmark) for bladder outlet obstruction in men unable to undergo transurethral resection of the prostate (TURP), assessing symptoms, complications and duration of stent life. Patients and methods The Memokath stent is a coil of a nickel-titanium alloy which has 'shape memory', the lower end expanding when heated to 55 degrees C. Risks associated with inserting the stent with a flexible cystoscope under local anaesthesia are minimal. Men were selected who were either permanently or temporarily unfit for TURP. Indications included severe respiratory and cardiovascular disease. Exclusion criteria included bladder carcinoma, calculi or detrusor failure; in all, 211 men were fitted with 217 intraprostatic stents over 8 years. Results There were 1511 TURPs during the study period; the mean age of men receiving a stent was 80.2 years, compared with 70.2 years for those undergoing TURP. The International Prostate Symptom Score decreased from a mean of 20.3 to 8.2 (P < 0.001) in the first 3 months after stent placement; there was virtually no change over 7 years. During the follow-up, 38% of men died with their stents in situ, 34% remain alive, 23% have had their stents removed for failure and 4% were removed as they were no longer required. There was a 13% migration rate and 16% repositioning rate. There were few side-effects (pain 3%, haematuria 3%, incontinence 6% and infection 6%). These frail men were more likely to die than have their stent fail. Conclusion The Memokath intraprostatic stent is a valuable addition to the armamentarium of the urologist treating elderly or frail men with advanced bladder outlet obstruction and complements existing technologies.
机译:目的评估热膨胀性前列腺内支架(Memokath(R),Engineers and Doctors A / S,丹麦哥本哈根)在无法进行经尿道前列腺电切术(TURP)的男性中的膀胱出口梗阻的使用,评估症状,并发症和支架寿命的持续时间。患者和方法Memokath支架是由镍钛合金制成的线圈,具有“形状记忆”功能,加热至55摄氏度时,其下端会膨胀。在局部麻醉下将其插入带有柔性膀胱镜的支架的风险极小。选择了永久或暂时不适合TURP的男性。适应症包括严重的呼吸道和心血管疾病。排除标准包括膀胱癌,结石或逼尿肌衰竭。总共有211名男性在8年中安装了217个前列腺内支架。结果研究期间共有1511个TURPs。接受支架的男性平均年龄为80.2岁,而接受TURP的男性为70.2岁。支架置入后的头三个月,国际前列腺症状评分从平均20.3降低至8.2(P <0.001);过去7年几乎没有变化。在随访过程中,有38%的男性因其原位支架而死亡,34%仍活着,23%的支架因故障而被拆除,4%的支架因不再需要而被拆除。迁移率为13%,重新安置率为16%。副作用很少(疼痛3%,血尿3%,尿失禁6%和感染6%)。这些脆弱的人死于支架失败的可能性更大。结论Memokath前列腺内支架是泌尿科医师设备库的重要补充,可治疗患有晚期膀胱出口梗阻的年老或体弱的男性,并补充了现有技术。

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