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首页> 外文期刊>International journal of dental hygiene >Effect of sonic versus manual supervised toothbrushing on both clinical and biochemical profiles of patients with desquamative gingivitis associated with oral lichen planus: A randomized controlled trial
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Effect of sonic versus manual supervised toothbrushing on both clinical and biochemical profiles of patients with desquamative gingivitis associated with oral lichen planus: A randomized controlled trial

机译：Sonic Versus监督牙刷对与口腔地衣直径相关的脱皮牙龈炎患者临床和生化曲线的影响：随机对照试验

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Abstract Objectives The aim of this randomized, parallel‐design, clinical trial was to investigate the effectiveness of an intensive plaque control programme with sonic versus manual toothbrushing on clinical outcomes and gingival crevicular fluid (GCF) levels of matrix metalloproteinases (MMP) in desquamative gingivitis (DG) patients. Methods A total of 32 patients affected by DG secondary to oral lichen planus (OLP) were consecutively recruited and randomly assigned to a test (n?=?16) and control (n?=?16) group. Both groups were enrolled in an intensive control programme comprising supragingival scaling and polishing, and brush‐specific instructions for a period of 8?weeks. The treatment of interest (test) was the use of a sonic‐powered toothbrush, and the standard treatment (control) was the utilization of a soft‐bristle manual toothbrush for twice‐daily home oral hygiene procedures. Periodontal parameters, patient‐centred outcomes, MMP‐1 and MMP‐9 GCF levels were evaluated at baseline and 8?weeks after starting the programme. Results The plaque control programme resulted in statistically significant reduction in periodontal parameters with consequent improvement in the clinical features, painful symptoms and severity of DG lesions in both groups (all P ??0.001). When a sonic toothbrush was used, there was a more significant decrease in clinical indices, mucosal disease scores and GCF levels of MMP‐1 and MMP‐9. Conclusions This clinical trial reported the effectiveness of a combined protocol based on professional oral hygiene and supervised toothbrushing in OLP patients with DG. The daily use of a sonic toothbrush would seem to perform better in the short term.
机译：摘要目的这一目标是随机，并行设计，临床试验的目的是调查密集斑块控制程序与Sonic Versus手动牙刷的有效性对Disquamative Gingivitis的基质金属蛋白酶（MMP）的临床结果和牙龈颈蛋白（GCF）水平（DG）患者。方法均连续招募和随机分配给次级地衣平面（OLP）对次级的DG次级的32例患者（N？=？16）和控制（n？=？16）组。两组都参加了一个密集的控制程序，包括Supritival缩放和抛光，以及刷特定的指令，为8？周。感兴趣的处理（测试）是使用声音动力的牙刷，标准治疗（控制）是利用软刷毛手动牙刷，用于两次每日口服卫生卫生程序。牙周参数，患者为中心的结果，MMP-1和MMP-9 GCF水平评估在基线和8个月后的8个星期。结果斑块控制程序导致牙周参数的统计学显着降低，随后在两组中改善了临床特征，疼痛症状和DG病变的严重程度（所有P？0.001）。当使用声音牙刷时，临床指数，粘膜疾病评分和MMP-1和MMP-9的GCF水平更显着降低。结论该临床试验报告了基于专业口腔卫生和DG患者的专业口腔卫生和监督牙刷的组合方案的有效性。每日使用声音牙刷在短期内似乎表现得更好。

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