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Applying 1-norm SVM with squared loss to gene selection for cancer classification

机译:将1常态SVM应用于CARMAR分类的基因选择

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摘要

Gene selection methods available have high computational complexity. This paper applies an 1-norm support vector machine with the squared loss (1-norm SVMSL) to implement fast gene selection for cancer classification. The 1-norm SVMSL, a variant of the 1-norm support vector machine (1-norm SVM) has been proposed. Basically, the 1-norm SVMSL can perform gene selection and classification at the same. However, to improve classification performance, we only use the 1-norm SVMSL as a gene selector, and adopt a subsequent classifier to classify the selected genes. We perform extensive experiments on four DNA microarray data sets. Experimental results indicate that the 1-norm SVMSL has a very fast gene selection speed compared with other methods. For example, the 1-norm SVMSL is almost an order of magnitude faster than the 1-norm SVM, and at least four orders of magnitude faster than SVM-RFE (recursive feature elimination), a state-of-the-art method.
机译:基因选择方法可用具有高计算复杂性。 本文适用一个带有平方损耗(1-NARM SVMSL)的1常态支持向量机,以实现癌症分类的快速基因选择。 已经提出了1-NARM SVMS1,已经提出了1常态支持向量机(1-NOM SVM)的变型。 基本上,1-NARM SVMSL可以在相同的情况下进行基因选择和分类。 但是,为了提高分类性能,我们只使用1-NARM SVMSL作为基因选择器,并采用后续分类器来分类所选基因。 我们在四个DNA微阵列数据集上进行广泛的实验。 实验结果表明,与其他方法相比,1-NARM SVMS1具有非常快的基因选择速度。 例如,1-NARM SVMSL几乎比1-NARM SVM快,并且比SVM-RFE(递归特征消除),最先进的方法,至少四个数量级。

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