...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International medical journal: IMJ >The association between the level of serum interleukin-31 (Il-31) and interleukin-33 (Il-33) and pruritus in patients with allergic diseases
【24h】

The association between the level of serum interleukin-31 (Il-31) and interleukin-33 (Il-33) and pruritus in patients with allergic diseases

机译：过敏性疾病患者血清白细胞介素-31（IL-31）和白细胞介素-33（IL-33）和瘙痒之间的关联

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

? 2016 Japan Health Sciences University & Japan International Cultural Exchange Foundation. ? 2016 Japan Health Sciences University & Japan International Cultural Exchange Foundation. Objectives: This study was done to determine the association between IL-31 and IL-33 serum levels and pruritus in patients with allergic diseases. Design: This was a comparative cross sectional study. Methods: Allergic diseases patients including atopic dermatitis (AD), allergic rhinitis (AR) and atopic asthma (AA) attending Hospital Universiti Sains Malaysia (HUSM) and Hospital Raja Perempuan Zainab II (HRPZ II), Malaysia were defined by history taken by physician. 5 ml of blood was collected and analyzed for IL-31 and IL-33 using ELISA kits (Human IL-31 and IL-33 Duoset, R&D System). One way ANOVA was used to compare the level of serum IL-31 and IL-33 between those with and without pruritus. Results: A total number of 210 allergic patients were included in this study. The results showed there was no significant difference in the mean level of IL-33 serum in non- pruritic (mean of 254.71, SD of 906.80) and in pruritic allergic patients (mean of 1219.61, SD of 8660.01, p = 0.156). There was also no significant difference in the mean level of IL-31 serum (p = 0.241). However, the level of IL-31 was higher in pruritic patients (mean of 6168.25; SD 30552.07) than in non-pruritic patients (mean of 3058.09, SD 12527.97). Conclusions: The results of this study suggest that there was no significant association between pruritus and the level of serum IL-31 and IL-33 in Malaysian allergic patients. Objectives: This study was done to determine the association between IL-31 and IL-33 serum levels and pruritus in patients with allergic diseases. Design: This was a comparative cross sectional study. Methods: Allergic diseases patients including atopic dermatitis (AD), allergic rhinitis (AR) and atopic asthma (AA) attending Hospital Universiti Sains Malaysia (HUSM) and Hospital Raja Perempuan Zainab II (HRPZ II), Malaysia were defined by history taken by physician. 5 ml of blood was collected and analyzed for IL-31 and IL-33 using ELISA kits (Human IL-31 and IL-33 Duoset, R&D System). One way ANOVA was used to compare the level of serum IL-31 and IL-33 between those with and without pruritus. Results: A total number of 210 allergic patients were included in this study. The results showed there was no significant difference in the mean level of IL-33 serum in non- pruritic (mean of 254.71, SD of 906.80) and in pruritic allergic patients (mean of 1219.61, SD of 8660.01, p = 0.156). There was also no significant difference in the mean level of IL-31 serum (p = 0.241). However, the level of IL-31 was higher in pruritic patients (mean of 6168.25; SD 30552.07) than in non-pruritic patients (mean of 3058.09, SD 12527.97). Conclusions: The results of this study suggest that there was no significant association between pruritus and the level of serum IL-31 and IL-33 in Malaysian allergic patients.
机译：还2016日本卫生科学大学＆amp;日本国际文化交流基金会。还2016日本卫生科学大学和日本国际文化交流基金会。目的：本研究已完成以确定IL-31和IL-33血清水平与过敏性疾病患者瘙痒之间的关联。设计：这是一个比较横断面研究。方法：过敏性疾病患者，包括特应性皮炎（AD），过敏性鼻炎（AR）和应诊医院HARSIA（HUSM）和医院Raja Perempuan Zainab II（HRPZ II），马来西亚的患者，马来西亚都被医师所采取的历史定义。收集5ml血液，并使用ELISA试剂盒（人IL-31和IL-33 Duoset，R＆amp; D系统）分析IL-31和IL-33。一种方式Anova用于比较有没有瘙痒的人之间的血清IL-31和IL-33的水平。结果：本研究纳入了210例过敏患者的总数。结果表明，非瘙痒（平均值为254.71，SD）和瘙痒过敏患者的IL-33血清的平均水平没有显着差异（平均值为1219.61，SD为8660.01，P = 0.156）。 IL-31血清的平均水平也没有显着差异（p = 0.241）。然而，瘙痒患者的IL-31水平较高（平均值为6168.25; SD 30552.07），而不是非瘙痒患者（平均值为3058.09，SD 12527.97）。结论：本研究结果表明，马来西亚过敏患者瘙痒和血清IL-31和IL-33水平之间没有显着关联。目的：本研究已完成以确定IL-31和IL-33血清水平与过敏性疾病患者瘙痒之间的关联。设计：这是一个比较横断面研究。方法：过敏性疾病患者，包括特应性皮炎（AD），过敏性鼻炎（AR）和应诊医院HARSIA（HUSM）和医院Raja Perempuan Zainab II（HRPZ II），马来西亚的患者，马来西亚都被医师所采取的历史定义。收集5毫升血液，并使用ELISA试剂盒（人IL-31和IL-33 Duoset，R＆D系统）分析IL-31和IL-33。一种方式Anova用于比较有没有瘙痒的人之间的血清IL-31和IL-33的水平。结果：本研究纳入了210例过敏患者的总数。结果表明，非瘙痒（平均值为254.71，SD）和瘙痒过敏患者的IL-33血清的平均水平没有显着差异（平均值为1219.61，SD为8660.01，P = 0.156）。 IL-31血清的平均水平也没有显着差异（p = 0.241）。然而，瘙痒患者的IL-31水平较高（平均值为6168.25; SD 30552.07），而不是非瘙痒患者（平均值为3058.09，SD 12527.97）。结论：本研究结果表明，马来西亚过敏患者瘙痒和血清IL-31和IL-33水平之间没有显着关联。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号