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Chemically-defined Natural Killer Cell Expansion Medium for Immunotherapy & Translational Research Applications Introduced

机译：用于免疫疗法和翻译研究应用的化学定义的自然杀伤细胞膨胀介质

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Irvine Scientific announces the introduction of PRIME-XV NK Cell CDM, the first commercially available chemically-defined (CDM), animal component-free (ACF) medium for the ex vivo expansion of NK cells. The advanced medium delivers natural killer (NK) cell expansion while preserving NK cell potency and functionality. Current approaches to immunotherapy focus on harnessing the power of the body's immune system to treat tumours with cell therapies. NK cells are one of the promising candidates as they have the potential to recognise and kill cancer cells. In fact, studies show NK cells possess the ability to identify certain tumour cells or virus-infected cells and destroy them by injecting cell-degrading proteins into the malignant cells. However, NK cells are not naturally abundant in vivo, which presents a significant obstacle to their use in NK-mediated therapies. The challenge is to produce sufficient numbers of cells ex vivo that are cytotoxic towards cancer cells to produce effective therapies.
机译：Irvine Scientific宣布推出Prime-XV NK细胞CDM，这是第一种商业化学定义（CDM），无动物组分（ACF）培养基，用于NK细胞的离体膨胀。先进的介质在保持NK细胞效力和功能的同时提供自然杀手（NK）细胞扩展。目前免疫疗法的措施，重点利用身体免疫系统的力量来治疗细胞疗法的肿瘤。 NK细胞是有希望的候选人之一，因为它们有可能识别和杀死癌细胞。事实上，研究显示NK细胞具有识别某些肿瘤细胞或病毒感染细胞的能力，并通过将细胞降解蛋白注入恶性细胞中来破坏它们。然而，NK细胞在体内并非自然丰富，这呈现了它们在NK介导的疗法中使用的显着障碍。挑战是产生足够数量的细胞离体，这是癌细胞的细胞毒性，以产生有效的疗法。

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