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Support Care Cancer 2007;15(6):643-7 [date of publication: June 2007] E. Chow, A. Loblaw, K. Harris, M. Doyle, P. Goh, H. Chiu, T. Panzarella, M. Tsao, E.A. Barnes, E. Sinclair, M. Farhadian, C. Danjoux Purpose: To investigate the efficacy of dexam-ethasone as a prophylactic adjuvant analgesic to decrease pain flare and to assess its safety and tolerance of dexamethasone. Materials and methods: Patients treated with a single 8 Gy for bone metastases took 8 mg dexamethasone before the radiation treatment. The Brief, Pain Inventory was administered at baseline and then daily for 10 days after radiation. Pain flare was defined as a two-point increase in the worst pain or a 25% increase in the analgesic intake when compared with the baseline.
机译:Support Care Cancer 2007; 15(6):643-7 [发布日期:2007年6月] E. Chow,A。Loblaw,K。Harris,M.Doyle,P.Goh,H。Chiu,T。Panzarella,M曹T巴恩斯(Barnes),辛克莱(E. Sinclair),法哈迪安(M. Farhadian),丹乔(C. Danjoux)目的:研究地塞米松作为预防性辅助镇痛药减少疼痛发作的功效,并评估其地塞米松的安全性和耐受性。材料和方法:接受单一8 Gy骨转移治疗的患者在放射治疗前服用了8 mg地塞米松。在基线时进行简短的疼痛清单,然后在放疗后每天进行10天。疼痛发作定义为与基线相比,最剧烈疼痛增加了两点,或者止痛剂摄入增加了25%。

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