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HIV infection epidemiology: a change of scenery

机译：艾滋病毒感染流行病学：风景的变化

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Combination antiretroviral therapy has completely changed the landscape of HIV infection through the control of viral replication of the virus, the restoration of the immune system damage, and the reduction of the complications associated with immunodeficiency. As a consequence, the average age of people living with HIV has been increasing progressively, with a high proportion of diagnosed, as well as newly diagnosed, HIV-infected patients being older than 50 years throughout the world. With the longer life expectancy, characteristics commonly observed in aging are occurring in people with long-term HIV infection, including multiple chronic diseases, changes in cognitive and physical abilities, and the use of multiple medications. HIV-related specific factors, as well as a higher prevalence of environmental, classical factors, increase the risk of comorbidities in the aging HIV-infected population. A close collaboration between different specialists (HIV specialists, geriatricians, primary care physicians, and other specialists) is required to manage the clinical problems that older HIV-infected patients may present.
机译：组合抗逆转录病毒治疗通过控制病毒的病毒复制完全改变了HIV感染的景观，恢复免疫系统损害，以及减少与免疫缺陷相关的并发症。因此，艾滋病毒患者的平均年龄逐渐增加，诊断的高比例和新诊断的艾滋病毒感染患者在全世界超过50年。随着寿命较长，常龄地观察到的特征是在长期HIV感染的人中发生，包括多种慢性疾病，认知和身体能力的变化以及多种药物的使用。艾滋病毒相关的特定因素，以及环境，古典因素的患病率较高，增加了衰老的艾滋病毒感染人群中的合并症的风险。需要在不同专家（艾滋病毒专家，老年人，初级保健医生和其他专家）之间密切​​合​​作，以管理较旧的艾滋病毒感染患者可能存在的临床问题。

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