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首页> 外文期刊>European Biophysics Journal >New wave-type mechanism of saltatory conduction in myelinated axons and micro-saltatory conduction in C fibres
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New wave-type mechanism of saltatory conduction in myelinated axons and micro-saltatory conduction in C fibres

机译:多纤维骨髓轴突中盐化传导的新波浪型机制及C纤维微盐传导

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摘要

We present a new wave-type model of saltatory conduction in myelinated axons. Poor conductivity in the neuron cytosol limits electrical current signal velocity according to cable theory, to 1-3 m/s, whereas saltatory conduction occurs with a velocity of 100-300 m/s. We propose a wave-type mechanism for saltatory conduction in the form of the kinetics of an ionic plasmon-polariton being the hybrid of the electro-magnetic wave and of the synchronized ionic plasma oscillations in myelinated segments along an axon. The model agrees with observations and allows for description of the regulatory role of myelin. It explains also the mechanism of conduction deficiency in demyelination syndromes such as multiple sclerosis. The recently observed micro-saltatory conduction in ultrathin unmyelinated C fibers with periodic ion gate clusters is also explained.
机译:我们介绍了一个新的骨髓轴突中的盐流传导型号模型。 神经元细胞溶溶胶中的导电性差根据电缆理论限制电流信号速度,达到1-3米/秒,而速度导通以100-300m / s的速度发生。 我们提出了一种用于离子等离子体 - 极性膜的动力学形式的盐类传导的波浪型机制是电磁波的混合和沿着轴突的骨髓段中的同步离子等离子体振荡。 该模型同意观察结果,并允许描述髓鞘的监管作用。 它还解释了脱髓鞘综合征等多发性硬化症的传导缺陷机制。 还解释了具有周期性离子栅极簇的超薄未髓鞘C纤维中最近观察到的微盐传导。

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