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首页> 外文期刊>Experimental and therapeutic medicine >Genotype distribution and the relative risk factors for human papillomavirus in Urumqi, China
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Genotype distribution and the relative risk factors for human papillomavirus in Urumqi, China

机译：基因型分布与乌鲁木齐人乳头瘤病毒的相对危险因素

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摘要

The aim of this study was to investigate human papillomavirus (HPV) infection and HPV genotype distributions in Urumqi, Xinjiang, China. The related risk factors for high-risk HPV infection was also analyzed. A stratified cluster sampling method was used for the population-based cervical cancer screening of women aged 18-69 years in the Urumqi Saybagh district. Exfoliated cervical cell samples were collected for liquid-based cytology detection and HPV genotyping DNA microarrays. Education level, number of sexual partners, condom use and occupation were used in the multivariate analysis model. The HPV infection rate of women working in service industries was significantly higher compared with those of white-collar workers, community residents and migrant workers. The 35-44-year-old migrant worker group had the highest HPV infection rates among all of the groups in the three different age ranges. The number of marriages, education level, smoking history, number of abortions, use of condoms, number of sexual partners, number of sexual partners in the past five years and occupation were all associated with female HPV infection rate (P0.05). The 35-44-year-old women were the age group with the highest HPV infection rate. The HPV infection rate of females in service industries was the highest. Education level and condom use were protective factors of HPV infection, while the number of sexual partners and occupation were risk factors for HPV infection.
机译：本研究的目的是探讨中国新疆乌鲁木齐的人乳头瘤病毒（HPV）感染和HPV基因型分布。还分析了高风险HPV感染的相关危险因素。利用分层的聚类取样方法用于乌鲁木齐的Saybagh区18-69岁妇女的群体宫颈癌筛查。收集剥离的宫颈细胞样品用于液体类细胞学检测和HPV基因分型DNA微阵列。在多变量分析模型中使用了教育水平，性伴侣，避孕套使用和职业的数量。与白领工人，社区居民和移民工人相比，在服务行业工作的妇女的HPV感染率明显高。 35-44岁的移民工人组在三个不同年龄范围内的所有群体中具有最高的HPV感染率。婚姻数量，教育水平，吸烟历史，堕胎数量，避孕套的数量，过去五年的性伴侣数量，性伴侣数量和职业都与女性HPV感染率有关（P <0.05）。 35-44岁的女性是HPV感染率最高的年龄组。服务行业中女性的HPV感染率最高。教育水平和避孕套使用是HPV感染的保护因素，而性伴侣和职业的数量是HPV感染的危险因素。

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  • 作者

    Chen Zhifang; Meng Wei; Du Rong; Zhu Yuejie; Zhang Yi; Ding Yan;

  • 作者单位

    Cent S Univ Xiangya Hosp Changsha 410000 Hunan Peoples R China;

    Xinjiang Med Univ Affiliated Hosp 1 Dept Gynecol Urumqi 830054 Xinjiang Peoples R China;

    Xinjiang Med Univ Affiliated Hosp 1 Dept Gynecol Urumqi 830054 Xinjiang Peoples R China;

    Xinjiang Med Univ Affiliated Hosp 1 Dept Gynecol Urumqi 830054 Xinjiang Peoples R China;

    Cent S Univ Xiangya Hosp Changsha 410000 Hunan Peoples R China;

    Xinjiang Med Univ Affiliated Hosp 1 Dept Gynecol Urumqi 830054 Xinjiang Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 治疗学;
  • 关键词

    human papillomavirus; genotype distribution; cervical cancer;

    机译：人乳头瘤病毒;基因型分布;宫颈癌;

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