Nrf2: a potential therapeutic target for naturally occurring anticancer drugs?

Catanzaro Elena; Calcabrini Cinzia; Turrini Eleonora; Sestili Piero; Fimognari Carmela

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Nrf2: a potential therapeutic target for naturally occurring anticancer drugs?

机译：NRF2：天然存在的抗癌药物的潜在治疗靶标？

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Introduction: Nuclear factor (erythroid-derived-2)-like 2 is one of the most efficient cytoprotective rheostats against exogenous or endogenous oxidative insults. At present, the modulation of the Nrf2 pathway represents an interesting and highly explored strategy in the oncological area.

机译：介绍：核因子（红细胞衍生的-2）-like 2是抗外源或内源性氧化损伤的最有效的细胞保护性变性剂之一。目前，NRF2途径的调节代表了肿瘤学区的有趣和高度探索的策略。

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《Expert opinion on therapeutic targets》 |2017年第12期|共13页
作者
Catanzaro Elena; Calcabrini Cinzia; Turrini Eleonora; Sestili Piero; Fimognari Carmela;
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作者单位

Alma Mater Studiorum Univ Bologna Dept Life Qual Studies Rimini Italy;

Alma Mater Studiorum Univ Bologna Dept Life Qual Studies Rimini Italy;

Alma Mater Studiorum Univ Bologna Dept Life Qual Studies Rimini Italy;

Univ Urbino Carlo Bo Dept Biomol Sci Urbino Italy;

Alma Mater Studiorum Univ Bologna Dept Life Qual Studies Rimini Italy;

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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
Nrf2; natural anticancer compounds; sulforaphane; resveratrol; brusatol; chemoresistance; chemosensitization; cancer chemoprevention and therapy;

机译：NRF2;天然抗癌化合物;磺酸盐;白藜芦醇;Brusatol;Chemiolatyistance;化学敏化;癌症化学预防和治疗;

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1. Nrf2: a potential therapeutic target for naturally occurring anticancer drugs? [J] . Catanzaro Elena, Calcabrini Cinzia, Turrini Eleonora, Expert opinion on therapeutic targets . 2017,第7a12期

机译：NRF2：天然存在的抗癌药物的潜在治疗靶标？
2. Enhancement of therapeutic potential of a naturally occurring human antibody targeting a phosphorylated Ser 422 containing epitope on pathological tau [J] . Jeroen van Ameijde, Rosa Crespo, Roosmarijn Janson, Acta Neuropathologica Communications . 2018,第1期

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4. THERAPEUTIC POTENTIAL OF NATURALLY OCCURRING FIBRIL-REACTIVE HUMAN ANTIBODIES FOR AL AMYLOIDOSIS [C] . B. ONuallain, A. Allen, T Richey, International Symposium on Amyloidosis . 2008

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5. Activity of Anticancer Drugs in Relation to the Tumour Microenvironment and Potential to Inhibit Repopulation and Enhance Therapeutic Outcome. [D] . Saggar, Jasdeep Kaur. 2014

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机译：Rhein作为潜在抗癌药物的治疗效果：对其分子靶标和抗癌性质的综述

Nrf2: a potential therapeutic target for naturally occurring anticancer drugs?

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