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Usual walking and obstacle avoidance are influenced by depressive and anxiety symptoms in patients with Parkinson's disease

机译:通常的行走和障碍避免受帕金森病患者抑郁和焦虑症状的影响

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Aim The aim of the present study was to analyze the association of depressive and anxiety symptoms with usual walking and obstacle avoidance in patients with Parkinson's disease. Methods Patients were divided into three groups: without depressive and anxiety symptoms ( n = 28); depressive symptoms only ( n = 15); and depressive and anxiety symptoms ( n = 19). Symptoms of depression and anxiety were evaluated by the Hospital Anxiety and Depression scale. Participants walked across a pathway in two experimental conditions: usual walking and obstacle avoidance. Kinematic data were recorded using an optoelectronic three‐dimensional system. Results During usual walking, the depressive and anxiety symptoms group presented shorter stride length and longer double support phase compared with the without depressive and anxiety symptoms group, and lower velocity than the without depressive and anxiety symptoms and depressive symptoms groups. During the approach phase of obstacle avoidance, the depressive and anxiety symptoms group decreased the stride length and velocity, whereas the without depressive and anxiety symptoms and depressive symptoms groups did not modulate these parameters. The depressive and anxiety symptoms group also showed shorter step length and velocity, longer step duration, and wider step width during obstacle crossing. Additionally, the depressive and anxiety symptoms group presented shorter foot‐to‐obstacle horizontal distances, and lower horizontal mean velocities during obstacle crossing. Partial correlation analyses showed that both depressive and anxiety symptoms were associated with spatiotemporal gait parameters. Conclusion Combined symptoms of depression and anxiety are associated with walking impairments in patients with Parkinson's disease in both usual walking and obstacle avoidance. Geriatr Gerontol Int 2019; 19: 868–873 .
机译:目的本研究的目的是分析帕金森病患者的常用行走和障碍症状的抑郁和焦虑症状的关联。方法将患者分为三组:没有抑郁和焦虑症状(n = 28);仅抑郁症状(n = 15);和抑郁和焦虑症状(n = 19)。医院焦虑和抑郁尺度评估了抑郁症和焦虑的症状。参与者在两个实验条件下走过一条途径:常用的行走和避免避免。使用光电三维系统记录运动数据。结果在常规行走过程中,与没有抑郁和焦虑症状组的无抑郁和焦虑症状组相比,抑郁和焦虑症状组呈现较短的立长长度和更长的双支撑阶段,以及比没有抑郁和焦虑症状和抑郁症状组的速度低。在避免障碍阶段的接近阶段,抑郁和焦虑症状组降低了升高的长度和速度,而没有抑郁和焦虑症状和抑郁症状组没有调节这些参数。抑郁和焦虑症状组还显示了较短的步长和速度,较长的阶梯持续时间,并且在障碍物交叉期间更宽的阶梯宽度。此外,抑郁和焦虑症状组呈现较短的脚踏障碍水平距离,并且在障碍物交叉期间较低的水平平均速度。部分相关分析表明,抑郁和焦虑症状既与时空步态参数都会有关。结论抑郁症和焦虑的联合症状与帕金森病患者在常规行走和障碍避免患者中的步伐障碍有关。 GeriaTr Gerontol int 2019; 19:868-873。

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