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首页> 外文期刊>FEMS Microbiology Ecology >In defence of Bacillus thuringiensis, the safest and most successful microbial insecticide available to humanity-a response to EFSA
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In defence of Bacillus thuringiensis, the safest and most successful microbial insecticide available to humanity-a response to EFSA

机译：在防御芽孢杆菌，最安全，最成功的微生物杀虫剂可用于人性 - 对EFSA的反应

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摘要

The Bacillus cereus group contains vertebrate pathogens such as B. anthracis and B. cereus and the invertebrate pathogen B. thuringiensis (Bt). Microbial biopesticides based on Bt are widely recognised as being among the safest and least environmentally damaging insecticidal products available. Nevertheless, a recent food-poisoning incident prompted a European Food Safety Authority review which argued that Bt poses a health risk equivalent to B. cereus, a causative agent of diarrhoea. However, a critical examination of available data, and this latest incident, provides no solid evidence that Bt causes diarrhoea. Although relatively high levels of B. cereus-like spores can occur in foods, genotyping demonstrates that these are predominantly naturally occurring strains rather than biopesticides. Moreover, MLST genotyping of >2000 isolates show that biopesticide genotypes have never been isolated from any clinical infection. MLST data demonstrate that B. cereus group is heterogeneous and formed of distinct clades with substantial differences in biology, ecology and host association. The group posing the greatest risk (the anthracis clade) is distantly related to the clade containing all biopesticides. These recent data support the long-held view that Bt and especially the strains used in Bt biopesticides are very safe for humans.
机译：芽孢杆菌组含有脊椎动物病原体，如B.炭疽病和B.培养物和无脊椎动物病原体B. thuringiensis（bt）。基于BT的微生物生物化学广泛认为是可用的最安全和最严重的环境损害杀虫产品之一。尽管如此，最近的食物中毒事件促使欧洲食品安全局审查，认为BT造成了与B.Cereus的健康风险，腹泻的致病因子。但是，对现有数据的关键检查以及这种最新事件，不提供BT导致腹泻的固体证据。虽然在食物中可能发生相对较高的B.麦芽饼孢子，但基因分型表明这些主要是天然存在的菌株而不是生物农药。此外，> 2000分离物的MLST基因分型表明生物农药基因型从未被从任何临床感染中分离出来。 MLST数据表明B.培养物组是异构的，由不同的曲线形成，具有实质性，生态和宿主协会的实质性差异。占据最大风险的小组（炭疽紫杉醇）与含有所有生物特产的思克彻底相关。这些最近的数据支持长期的视图，即BT生物农药中使用的BT和尤其是人类对人类非常安全的。

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