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A systematic review on the rhizome of Ligusticum chuanxiong Hort. (Chuanxiong)

机译:川芎雄勋根茎系统综述。 (川芎)

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摘要

Chuanxiong Rhizome (called Chuanxiong, CX in Chinese), the dried rhizome ofLigusticum chuanxiongHort, is an extremely common traditional edible-medicinal herb. As a widely used ethnomedicine in Asia including China, Japan and Korea, CX possesses ideal therapeutic effect on cardiovascular and cerebrovascular diseases, and is also used as a major ingredient in soups for regular consumption to benefit health. Based on the traditional perception, amounts of investigations on different aspects have been done for CX in the past decades. However, no literature systematic review about these achievements have been compiled. Herein, the aim of this review is to present the up-to-date information on the ethnobotany, ethnopharmacological uses, phytochemicals, pharmacological activities, toxicology of this plant to identify their therapeutic potential and directs future research opportunities. So far, about 174 compounds has been isolated and identified from CX, in which phthalides and alkaloids would be the main bioactive ingredients for its pharmacological properties, such as anti-cerebral ischemia, anti-myocardial ischemia, blood vessel protection, anti-thrombotic, anti-hypertensive, anti-atherosclerosis, anti-spasmodic, anti-inflammatory, anti-cancer, anti-oxidant, and anti-asthma effects. Even so, due to the incomplete standardized planting, unstable herbal quality, and outdated preparation techniques, the industrial progress of CX is still less developed.
机译:川芎根茎(称为川芎,CX中文),川芎的干根茎是一种极其常见的传统食用药草。作为中国,日本和韩国在内的亚洲的广泛使用的民族医疗,CX对心血管和脑血管疾病具有理想的治疗效果,也被用作汤中的主要成分,以便常规消费受益。根据传统的感知,在过去的几十年中,CX已经为不同方面进行了调查量。但是,没有关于这些成就的文献系统审查已经编制。在此,本综述的目的是介绍关于乙醛,民族医药机,植物理学,植物理学,药理活动,该植物的毒理学,以确定其治疗潜力并指导未来的研究机会。到目前为止,已经从CX分离并鉴定了约174种化合物,其中邻苯二甲酸和生物碱是其药理学性质的主要生物活性成分,例如抗脑缺血,抗心肌缺血,血管保护,抗血栓形成,抗血栓形成,抗高血压,抗动脉粥样硬化,抗痉挛,抗炎,抗癌,抗氧化剂和抗哮喘效应。即便如此,由于规范化种植不完全,草药质量不稳定,制备技术过时,CX的工业进步仍然不那么开发。

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