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首页> 外文期刊>Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology >Impact of overt diabetes diagnosed in pregnancy in a multi-ethnic cohort in Spain
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Impact of overt diabetes diagnosed in pregnancy in a multi-ethnic cohort in Spain

机译：西班牙多种族队列怀孕术治疗妊娠的影响

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Overt diabetes (ODM) is defined as women without diabetes meeting the criteria for diabetes at the first antenatal visit. The risk of obstetric complications increases linearly with maternal glycemia and poorer maternal-fetal outcomes than in gestational diabetes (GDM) may be expected. Studies focusing on ODM pregnancy outcomes are lacking. We aimed to analyze maternal characteristics and pregnancy outcomes in ODM women compared with those with GDM. A retrospective cohort study of women giving birth between January 2010 and April 2013 was conducted. Participants with pre-gestational diabetes were excluded. All women underwent screening for GDM at the 24th-28th weeks of gestation or at the first prenatal visit in those with risk factors. HbA1c and a fasting glucose were measured in GDM women to rule out ODM. Of the 5,633 women included, 572 (10%) were diagnosed with GDM and 50 (0.88%) with ODM. Almost 95% of ODM women were from ethnic minorities. After adjustment for confounding factors, ODM women showed increased rates of premature birth (23.1% vs. 6.7%, p<.001), emergent cesarean section (41.0% vs. 19.5%, p = .049), preeclampsia (22% vs. 3.7%, p<.001) and large-for-gestational-age babies (40.0% vs. 14.8%, p = .008) compared with GDM. In conclusion, ODM is associated with poorer obstetric outcomes than GDM and affects mainly women from ethnic minorities.
机译：公开糖尿病（ODM）被定义为没有糖尿病的女性，符合第一次产前访问的糖尿病标准。产妇糖血症的产科并发症的风险增加，并且可能预期孕妇胎儿结果比妊娠期糖尿病（GDM）。缺乏关注ODM妊娠结果的研究。与GDM的人相比，我们旨在分析ODM女性的母体特征和妊娠结果。进行了2010年1月和2013年4月在2013年1月至2013年4月之间出生的审查队列研究。除了妊娠前糖尿病的参与者被排除在外。所有女性在妊娠24日 - 28日或在危险因素的第一次孕产阶级访问时，所有妇女都在筛选GDM。在GDM妇女中测量HBA1C和空腹葡萄糖以排除ODM。在包括的5,633名中，572名（10％）被诊断为GDM和50（0.88％），ODM。近95％的ODM妇女来自少数民族。在对混淆因素进行调整后，ODM妇女表现出早产的提高（23.1％vs.6.7％，p <.001），新罕布什尔省（41.0％与19.5％，P = .049），预普拉姆（22％VS）（22％VS与GDM相比，3.7％，P <.001）和大胎龄婴儿（40.0％与14.8％，P = .008）。总之，ODM与产科差异较差的产科结果相关，并影响少数民族的妇女。

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