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首页> 外文期刊>Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology >Ovarian hyperstimulation syndrome: a clinical retrospective study on 565 inpatients
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Ovarian hyperstimulation syndrome: a clinical retrospective study on 565 inpatients

机译：卵巢过度刺激综合征：565位存分病的临床回顾性研究

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The aim of this study was to analyze clinical manifestations of 565 ovarian hyperstimulation syndrome (OHSS) inpatients in the largest Obstetrics and Gynecology hospital in China from year 2010 to 2017, to get more understanding of epidemiologic features of this disease, and to provide some insight on the diagnosis, treatment, and preventions of OHSS. It is a clinical retrospective study. In the 565 cases that developed OHSS over an eight-year period between 2010 and 2017 were reviewed, we assessed patients' general characteristics, clinical manifestations, treatment, prognosis, and the relationship between different indicators and the severity of OHSS. Totally 12 kinds of ovulation induction protocols (Protocol 1: CC; Protocol 2: Gn; Protocol 3: hCG; Protocol 4: GnRh-a; Protocol 5: CC & Gn; Protocol 6: CC & hCG; Protocol 7: Gn & hCG; Protocol 8: GnRh-a & Gn; Protocol 9: CC & Gn & hCG; Protocol 10: GnRh-a & CC & Gn; Protocol 11: Letrozole & Gn & hCG; Protocol 12:GnRh-a & Letrozole & Gn) were analyzed and the Odds Ratio (OR) of each protocol were calculated. Five hundred and sixty-five patients were reviewed in our study. In all these patients, the number of hospitalizations, mean age, primary infertility rate, and pregnancy rate did not differ through the last 8 years. From which we may infer that the incidence rate of OHSS may not change over the last 8 years. Older patients tend to develop into more severe stage easily. The pregnancy rate was much lower in mild stage patients, but no difference was found between patients in moderate, severe and critical stage. Oocytes retrieval is strongly associated with severity. PCOS history, irregular menstrual cycle and infertility type do not seem to affect the severity of OHSS. Twelve kinds of ovulation induction protocols were analyzed, OR of different protocols were calculated, what is noteworthy is that patients who used GnRh easily developed more severe OHSS than the patients who received oocytes retrieval. We suggest that we may choose ovulation induction protocols according to the OR table while treating women with high-risk factors.
机译：本研究的目的是在2010年至2017年期间分析中国最大的妇产科医院565卵巢过度刺激综合征（OHSS）住院患者的临床表现，以便更多地了解这种疾病的流行病学特征，并提供一些见解论OHSS的诊断，治疗和预防。这是一个临床回顾性研究。在2010年至2017年间八年期间开发了565例，我们评估了患者的一般特征，临床表现，治疗，预后，以及不同指标与OHSS的严重程度之间的一般特征，临床表现，治疗，预后和关系。完全12种排卵感应方案（方案1：CC;协议2：GN;协议3：HCG;协议4：GNRH-A;协议5：CC＆GN;协议6：CC＆HCG;协议7：GN＆HCG ;协议8：GNRH-A＆GN;协议9：CC＆GN＆HCG;协议10：GNRH-A＆CC＆GN;方案11：Letrozole＆Gn＆Hcg;协议12：GnRH-A和Letrozole＆Gn）分析并计算每种方案的差距（或）。在我们的研究中审查了五百六十五名患者。在所有这些患者中，住院时间，平均年龄，主要不孕症率和怀孕率在过去的8年里没有任何不同。从中，我们可以推断ohss的发病率可能不会在过去的8年内发生变化。老年患者倾向于轻松发展到更严重的阶段。轻度阶段患者的妊娠率低得多，但在中度，严重和临界阶段之间没有发现患者之间的差异。卵母细胞检索与严重程度密切相关。 PCOS历史，不规则月经周期和不孕症类型似乎不会影响OHSS的严重程度。分析了12种排卵感应协议，或计算不同的协议，值得注意的是，使用GNRH的患者比接受卵母细胞检索的患者容易发生更严重的ohs。我们建议我们可以根据或桌子选择排卵感应协议，同时治疗具有高风险因素的妇女。

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