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首页> 外文期刊>Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology >The effect of myoinositol on ovarian blood flows in women with polycystic ovary syndrome
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The effect of myoinositol on ovarian blood flows in women with polycystic ovary syndrome

机译：肌肌醇对多囊卵巢综合征妇女卵巢血液流动的影响

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摘要

To evaluate whether 4 gram myoinositol and 400 mcg folic acid(MYO) therapy has any effects on ovarian stromal blood flow by using pulsed and color Doppler at 3 months follow-up period in polycystic ovary syndrome (PCOS). One-hundred eighty patients were designed into six groups; Group 1: PCOS patients that received OCP containing 30 mcg ethinyl estradiol (EE) plus 3mg drospirenone (DRP); Group 2: PCOS patients that received MYO; Group 3: PCOS patients that received no medication. Group 4: Healthy patients that received OCP; Group 5: Healthy patients that received MYO; Group 6: Healthy patients that received no medication. Resistance index (Rl) and pulsatility index (PI) of both ovaries were assessed. There was a significant increase in Rl and PI of both ovarian stromal blood flow women with PCOS who received OCP (Group 1, p<.001) and MYO (Group 2, p<.001). The rate of increment in both Rl and PI values were similar for OCP users (Group 1) and MYO users(Group2) in PCOS patients. MYO therapy reduced ovarian vascularization in both PCOS and healthy users after 3 months and this decrease is especially noticeable in women with PCOS compared to healthy women. OCP therapy also reduced ovarian vascularization just like MYO therapy.
机译：为了评估4克肌肌醇和400毫克叶酸（MyO）治疗是否通过在3个月在多囊卵巢综合征（PCOS）中的3个月随访期间对卵巢分子血流具有任何影响。一百八个患者设计成六组;第1组：PCOS患者接受含有30mcg乙基雌二醇（EE）加3mg甲卓酮（DRP）的OCP;第2组：PCOS接受MYO的患者;第3组：PCOS患者，没有药物。第4组：接受OCP的健康患者;第5组：接受Myo的健康患者;第6组：没有药物的健康患者。评估两种卵巢的抗性指数（RL）和脉动性指数（PI）。接受OCP的PCOS（第1组，P <.001）和MyO（第2组，P <.001），卵巢基质血流妇女的RL和PI患有卵巢基质血流量妇女的显着增加。 RL和PI值中的增量率类似于PCOS患者的OCP用户（第1组）和Myo用户（Group2）。 Myo治疗在3个月后在PCOS和健康用户中减少卵巢血管化，与健康女性相比，PCOS的妇女尤其明显。 OCP疗法也只是像Myo治疗一样减少卵巢血管化。

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