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首页> 外文期刊>Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology >Women with extreme low AMH values could have in vitro fertilization success
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Women with extreme low AMH values could have in vitro fertilization success

机译：极低的AMH值的女性可能会有体外施肥成功

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摘要

Circulating anti-mullerian hormone (AMH) and antral follicle count (AFC) are the best predictors of IVF outcomes. However, in extreme low AMH range especially for young patients, AMH prediction power loose its specificity to give real idea of pregnancy chance with IVF treatments and good prognosis of an extremely reduced ovarian reserve and expected poor response. Indeed, this retrospective study was conducted to evaluate IVF outcomes in patients following IVF-ICSI program with extremely low AMH levels (<0.4ng/ml; n = 390) compared to those presenting normal AMH range (1.3-2.6 ng/ml; n = 352) considered as control group. As expected, number of oocytes retrieved per patient, and embryological outcomes were significantly lower in the extremely low AMH levels group compared to control. Moreover, it was same trend concerning clinical outcomes but we have to note that even in extreme low AMH, patients could reach ineligible satisfying clinical pregnancy rate compared to control (17% vs 41%). For patients younger than 35 years, clinical pregnancy rate improved to 27%. Women with extreme low AMH values and especially younger ones, still have reasonable chances of achieving pregnancy, highlighting the default view of this category generally excluded from IVF program.
机译：循环抗Mullerian激素（AMH）和Antral卵泡计数（AFC）是IVF结果的最佳预测因子。然而，在极端低的AMH范围内特别适用于年轻患者，AMH预测权力松散其特异性，使IVF治疗的妊娠机会的真实理念和极其降低的卵巢储备的预后和预期的良好反应。实际上，在与呈现正常AMH范围（1.3-2.6ng / ml; n = 352）被视为对照组。与对照相比，每位患者检出的卵母细胞的数量和胚胎学结果显着降低，与对照相比，极低的AMH水平组显着降低。此外，它与临床结果相同，但我们必须注意到，即使在极端低中，患者也可以与对照（17％vs 41％）相比，患者可以达到不合格的临床妊娠率。对于35岁以上的患者，临床妊娠率将提高到27％。患有极端低AMH值的妇女，特别是较年轻的妇女，仍然有合理的旨在实现怀孕的机会，突出了通常从IVF计划中排除的此类别的默认视图。

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