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首页> 外文期刊>Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology >Can we predict oocyte maturation prior to denudation for intracytoplasmic sperm injection?
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Can we predict oocyte maturation prior to denudation for intracytoplasmic sperm injection?

机译：我们可以在剥落前预测卵母细胞成熟以进行顽固的精子注射吗？

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Intracytoplasmic sperm injection (ICSI) was introduced in 1992 as a method to treat couples with severe male infertility. However, in the last two decades, the use of ICSI has increased substantially even among patients without male factor infertility. In ICSI the oocytes are scrutinized for maturity upon insemination and the immature oocytes are discarded. The aim of the present study was to assess the ability of an experienced embryologist to identify the maturity of the oocytes prior to their denudation. In the present prospective observational study, four experienced embryologists examined the oocytes prior to their denudation and decided whether the oocytes were mature or immature. Later, the oocytes were denudated and the embryologist again examined the oocytes to confirm their prior assumptions. 483 oocytes were examined by four embryologists. Three hundred and fifty one of the oocytes were mature (72.7%) and 132 were immature (27.3%). The embryologists were able to correctly identify oocytes maturation status in 85.3% of cases. The embryologists were able to correctly identify 90% of the mature oocytes and 72.7% of the immature oocytes. When they assumed that the oocytes were mature they were correct in 89.% of the cases, while only 74.6% of their prediction that the oocytes were immature were true. To conclude, the embryologists are able to identify the oocytes maturation status before denudation at the majority of the cases. Whenever the oocytes are suspected to be immature, further consideration should be made whether to proceed to ICSI or not.
机译：1992年引入了Intractictoplasmic精子注射（ICSI）作为治疗伴侣的方法，具有严重的男性不孕症。然而，在过去二十年中，即使在没有男性因子不孕症的患者中，ICSI的使用就会大大增加。在ICSI中，卵母细胞被审查以在授精时成熟，并且丢弃未成熟的卵母细胞。本研究的目的是评估经验丰富的胚胎学家在剥落之前识别卵母细胞成熟度的能力。在目前的观察性研究中，四名经验丰富的胚胎学家在剥落之前检查了卵母细胞，并决定卵母细胞是否成熟或未成熟。后来，卵母细胞被剥蚀，胚胎学家再次检查卵母细胞以确认其先前的假设。 483个胚胎学检查了483名胚胎学。三百五十个卵母细胞成熟（72.7％），132个不成熟（27.3％）。胚胎学家能够在85.3％的情况下正确鉴定卵母细胞成熟状态。胚胎学家能够正确鉴定成熟卵母细胞的90％和72.7％的未成熟卵母细胞。当他们认为卵母细胞成熟时，它们在89.％的情况下正确，而卵母细胞未成熟的预测只有74.6％是真实的。为了得出结论，胚胎素医生能够在大多数情况下剥落之前识别卵母细胞成熟状态。每当怀疑卵母细胞未成熟时，应进一步考虑是否进入ICSI。

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