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Regional differences in milk and complementary feeding patterns in infants participating in an international nutritional type 1 diabetes prevention trial

机译:参与国际营养1型糖尿病预防审判的婴儿牛奶和互补饲养模式的区域差异

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Abstract Differences in breastfeeding, other milk feeding and complementary feeding patterns were evaluated in infants at increased genetic risk with and without maternal type 1 diabetes (T1D). The Trial to Reduce IDDM in the Genetically at Risk is an international nutritional primary prevention double‐blinded randomized trial to test whether weaning to extensively hydrolyzed vs. intact cow's milk protein formula will decrease the development of T1D‐associated autoantibodies and T1D. Infant diet was prospectively assessed at two visits and seven telephone interviews between birth and 8?months. Countries were grouped into seven regions: Australia, Canada, Northern Europe, Southern Europe, Central Europe I, Central Europe II and the United States. Newborn infants with a first‐degree relative with T1D and increased human leukocyte antigen‐conferred susceptibility to T1D were recruited. A lower proportion of infants born to mothers with than without T1D were breastfed until 6?months of age in all regions (range, 51% to 60% vs. 70% to 80%). Complementary feeding patterns differed more by region than by maternal T1D. In Northern Europe, a higher proportion of infants consumed vegetables and fruits daily compared with other regions. Consumption of meat was more frequent in all European regions, whereas cereal consumption was most frequent in Southern Europe, Canada and the United States. Maternal T1D status was associated with breastfeeding and other milk feeding patterns similarly across regions but was unrelated to the introduction of complementary foods. Infant feeding patterns differed significantly among regions and were largely inconsistent with current recommended guidelines.
机译:摘要在婴儿中评估母乳喂养和互补喂养模式的差异,随着母体1型糖尿病(T1D)增加遗传风险。审判在遗传上减少IDDM的风险是一种国际营养初级预防双盲随机试验,以测试是否被广泛水解的与完整的牛奶蛋白配方发生断奶,将降低T1D相关的自身抗体和T1D的发育。婴儿饮食在两次访问和出生之间和8个月之间进行了七个电话访谈。各国被分成七个地区:澳大利亚,加拿大,北欧,南欧,中欧,中欧II,中欧和美国。招募了新生儿,具有一定程度的T1D和增加的人白细胞抗原赋予T1D的抗原易感性。母乳喂养的母亲较低的婴儿比例较低,直到所有地区的6?几个月(范围,51%〜60%〜80%)。互补喂养模式逐个区域不同于母体T1D。在北欧,与其他地区相比,婴儿消耗蔬菜和水果的比例较高。所有欧洲地区的肉类消耗更频繁,而谷物消费在欧洲南部,加拿大和美国最常见。母亲T1D状态与地区同样地与母乳喂养和其他牛奶饲养模式相关联,但与引入互补食品无关。地区之间的婴儿喂养模式显着不同,并且与当前建议的准则相比,主要不一致。

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