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A primary investigation of the relation between the incidence of brucellosis and climatic factors in Iran

机译:伊朗布鲁氏菌病发病率与气候因子关系的初步调查

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Brucella spp. are Gram-negative coccobacilli that may grow in different media and environmental conditions for extended periods of time. The survivals of these bacteria in the environment have an important impact on the epidemiology of brucellosis worldwide. The effect of climate on the incidence of certain zoonotic infectious diseases, (recently referred to as climate-sensitive zoonosis) is now well established. The aim of this study was to evaluate the relation between the incidence of brucellosis and climatic parameters in Iran, an important endemic region for brucellosis with diverse climate. The information on the incidence of human brucellosis in different Iranian provinces for 2016 has been provided by the Ministry of Health and Medical Education, Iran. Annual meteorological data collected between 2015 and 2016 were obtained from the Iranian Meteorological organization (IMO). A regression analysis of the incidence of brucellosis was performed via STATA 14.0 and the heterogeneity among observations was determined via Cochrane's Q-test and I-2 statistic. If I-2 index was higher than 50%, heterogeneity was considered as considerable. The results of regression analyses revealed a negative significant association between mean ambient air temperature and brucellosis incidence (C = - 0.022, P value = 0.004). Likewise, a positive significant association was found between number of frosty days and brucellosis incidence (C = 0.002, p value = 0.003). Other metrological parameters showed no significant effect on the human brucellosis incidence. Although our results suggest a high degree of temperature sensitivity in regards to the brucellosis incidence in Iran, this study opens up prospects for further investigations regarding environmental conditions and climatic changes influencing the spatial distributions and seasonal/annual cycle of this zoonotic pathogen worldwide.
机译:布鲁氏菌SPP。是革兰氏阴性的coccobacilli,可在不同的媒体和环境条件下长时间生长。这些细菌在环境中的幸存者对全世界布鲁氏菌病的流行病学产生了重要影响。气候对某些人畜共患病发生率的影响(最近被称为气候敏感的人群病症)现在已经很好地建立了。本研究的目的是评估伊朗的布鲁氏菌病和气候参数的发生率,这是一种不同的气候的重要条目区域。伊朗卫生和医学教育部提供了关于2016年不同伊朗省的人体布鲁氏发病率的信息。 2015年至2016年间收集的年度气象数据是从伊朗气象组织(IMO)获得的。通过STATA 14.0进行BRucellosis的发生率的回归分析,并通过Cochrane的Q-Test和I-2统计测定观察结果之间的异质性。如果I-2指数高于50%,则异质性被认为是可观的。回归分析结果揭示了平均环境空气温度和布鲁氏菌发病率之间的负显着关联(C = - 0.022,P值= 0.004)。同样地,在寒冷的日子和布鲁氏菌病的数量和布鲁氏分泌发生率之间发现阳性重要关联(C = 0.002,P值= 0.003)。其他计量参数对人体布鲁氏发病率没有显着影响。虽然我们的结果表明,对伊朗的布鲁氏菌病发病率的高度温度敏感性,但这项研究开辟了关于环境条件和气候变化的进一步调查,影响了全世界该动物园病原体的空间分布和季节性/年周期的进一步调查。

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