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首页> 外文期刊>European Journal of Surgical Oncology: The Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology >Does high body mass index negatively affect the surgical outcome and long-term survival of gastric cancer patients who underwent gastrectomy: A systematic review and meta-analysis
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Does high body mass index negatively affect the surgical outcome and long-term survival of gastric cancer patients who underwent gastrectomy: A systematic review and meta-analysis

机译：高体重指数是否会影响接受胃切除术的胃癌患者的手术结果和长期存活：系统审查和荟萃分析

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BackgroundWhether high body mass index (BMI) was associated with increased postoperative complications and unfavorable prognosis of gastric cancer (GC) patients remain controversial. In the present study, we performed a systematic review and meta-analysis to evaluate the impact of high BMI on surgical outcome, postoperative complications and long-term survival of GC patients. MethodsThe related studies were identified by searching PubMed and Embase databases. According to the BMI, all GC patients were classified into BMI ≥25?kg/m2group and BMI <25?kg/m2group. The relevant data was extracted and pooled effect size was assessed using a fixed effect model or random effect model. ResultsA total of 36 relevant studies involving 30,642?GC patients were included in this meta-analysis. The results indicated that high BMI patients had longer operation time, fewer number of retrieved lymph nodes and larger amount of intraoperative blood loss than other patients, regardless of open gastrectomy or laparoscopic gastrectomy. In addition, the risk of postoperative complications was significantly higher in the patients with BMI ≥25?kg/m2than in those with BMI <25?kg/m2, especially for infectious complications. However, high BMI had no negative impact on postoperative mortality and long-term survival of GC patients. ConclusionDespite the increased surgical difficulty and postoperative complications, high BMI was not associated with the prognosis of GC patients. To reduce the risk of postoperative complications, more meticulous operation technique and improved perioperative management should be necessary for high BMI patients.
机译：背景高体重指数（BMI）与术后并发症增加有关，胃癌（GC）患者的不利预后仍然存在争议。在本研究中，我们进行了系统审查和荟萃分析，以评估高BMI对GC患者的手术结果，术后并发症和长期存活的影响。通过搜索PubMed和Embase数据库来确定相关研究。根据BMI，所有GC患者均分为BMI≥25？kg / m2group和bmi <25？kg / m2group。提取相关数据并使用固定效果模型或随机效果模型评估汇总效果大小。结果总共36项相关研究涉及30,642次患者患者纳入该荟萃分析。结果表明，高BMI患者的操作时间较长，检索淋巴结数量较少，术中失血量比其他患者更大，无论开放的胃切除术或腹腔镜胃切除术。此外，BMI≥25克/ M2在具有BMI <25 kg / m2的人中，术后并发症的风险显着高，特别是对于传染性并发​​症。然而，高BMI对术后死亡率和GC患者的长期存活没有负面影响。结论陈述增加的外科难度和术后并发症，高BMI与GC患者的预后无关。为了降低术后并发症的风险，高BMI患者应该需要更细致的操作技术和改善的围手术期管理。

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