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Hypertensive disorders of pregnancy and risks of adverse pregnancy outcomes: a retrospective cohort study of 2368 patients

机译:怀孕的高血压障碍和不良妊娠的风险:2368例患者的回顾性队列研究

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摘要

Hypertensive disorders of pregnancy (HDP) comprise a group of hypertension-related diseases and represent the most common medical disorders in pregnancy. The aim of this study was to investigate the risks of adverse pregnancy outcomes in patients with different types of HDP, including gestational hypertension, chronic hypertension, preeclampsia (PE, early or late onset), PE superimposed on chronic hypertension (superimposed PE), eclampsia, and HELLP syndrome. Data from a multicenter retrospective patient cohort in China were analyzed. Seventeen adverse maternal or perinatal outcomes were evaluated. Logistic regression was used to estimate the risk of adverse outcomes for each HDP subgroup, using the gestational hypertension group as the reference. The final analysis included 2368 patients with HDP. Of these, 39.9% of patients reported at least one adverse pregnancy outcome. Patients with early onset PE had the highest risk for having both adverse maternal and perinatal outcomes (OR = 7.28,95% Cl: 2.68,19.79).
机译:怀孕的高血压疾病(HDP)包含一组与高血压相关的疾病,并代表怀孕中最常见的医学障碍。本研究的目的是探讨不同类型的HDP患者的不利妊娠结果的风险,包括妊娠高血压,慢性高血压,预填血(PE,早期或晚期),PE叠加在慢性高血压(叠加PE),Eclampsia上叠加和hellp综合征。分析了中国多中心回顾性患者队列的数据。评估了17个不良母体或围产期结果。使用妊娠期高血压组作为参考,使用逻辑回归来估算每个HDP亚组的不良结果的风险。最终分析包括2368例HDP患者。其中,39.9%的患者报告了至少一个不良怀孕结果。早期发病PE的患者具有不良母体和围产期结果的风险最高(或= 7.28,95%CL:2.68,19.79)。

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