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首页> 外文期刊>Knee surgery, sports traumatology, arthroscopy: official journal of the ESSKA >Infection and revision rates following primary total knee arthroplasty in patients with rheumatoid arthritis versus osteoarthritis: a meta-analysis
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Infection and revision rates following primary total knee arthroplasty in patients with rheumatoid arthritis versus osteoarthritis: a meta-analysis

机译：类风湿性关节炎患者与骨关节炎患者的初级总膝关节置换术后感染和修订率：META分析

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Abstract Purpose This meta-analysis compared infection and revision rates in patients with rheumatoid arthritis (RA) and osteoarthritis (OA) who underwent total knee arthroplasty (TKA). Rates of superficial wound and deep periprosthetic infections were compared in the groups, as were whether revision rates associated with infectious and noninfectious causes differed in the RA and OA groups. Methods Studies were included in the meta-analysis if they (1) compared infection and revision rates after primary TKA in RA and OA patients; (2) directly compared superficial wound and deep periprosthetic infection rates in RA and OA patients who underwent primary TKA; and (3) reported the actual numbers of RA and OA patients who underwent TKA and developed postoperative infection and/or required revision. Results The rate of superficial wound infections after primary TKA was similar in the RA and OA groups (15/258 [5.8?%] vs. 77/1609 [4.7?%]; odds ratio [OR] 1.12, 95?% confidence interval [CI] 0.36–3.46; P ?=?n.n.), but the deep infection rate was significantly higher in RA than in OA patients (229/7651 [3.0?%] vs. 642/68628 [0.9?%]; OR 2.04, 95?% CI 1.37–3.05; P ? P ? P ?=?n.n.) Conclusion Following primary TKA, RA patients had a significantly higher rate of deep periprosthetic infections than OA patients, but their superficial infection rates were similar. The revision rate due to infectious causes was significantly higher in RA than in OA patients, but their revision rates due to noninfectious causes did not differ. Therefore, the surgeon should fully explain to RA patients scheduled to undergo primary TKA that, compared to OA patients,?they are more likely to experience a deep infection postsurgery. Level of evidence Meta-analysis Level III.
机译：摘要目的这种荟萃分析与类风湿性关节炎（RA）和骨关节炎（OA）患者的患者进行了比较的感染和修订率（TKA）。在组中比较了浅表伤口和深周期性感染的速率，以及RA和OA组中是否与传染性和非排感原因相关的修正率。方法在雷达和OA患者中初级TKA后的感染和修订率（1）（1），纳入研究中包括研究。 （2）在初级TKA的RA和OA患者中直接比较浅表伤口和深处颅脑细胞感染率; （3）报告了经过TKA的RA和OA患者的实际数量，并开发出术后感染和/或要求修订。结果初级TKA后浅表伤口感染的速率在RA和OA组中相似（15/258 [5.8〜5.8□]与77/1609 [4.7？％];赔率比[或] 1.12,95？％置信区间[CI] 0.36-3.46; p？=？nn），但RA的深度感染率明显高于OA患者（229/7651 [3.0〜7.0倍] [0.9吗？％];或2.04 ，95？％CI 1.37-3.05; p？p？p？=Δnn）结论后，初级TKA后，RA患者比OA患者的深层衰退感染率明显较高，但它们的浅表感染率相似。 RA患者的传染性原因导致的修订率明显高于OA患者，但由于非福利原因导致的修订率没有差异。因此，外科医生应充分解释于安排经过初级TKA的RA患者，与OA患者相比，它们更有可能经历深入的感染后期医学。证据级别荟萃分析级别III。

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