...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Nanoscience and Nanotechnology Letters >Light-Activated Nanoparticles Encapsulated with Santalum Album: A Potential Therapeutic Agent for Neurodegenerative Disease
【24h】

Light-Activated Nanoparticles Encapsulated with Santalum Album: A Potential Therapeutic Agent for Neurodegenerative Disease

机译：用Santalum专辑包封的光活性纳米粒子：神经变性疾病的潜在治疗剂

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Sandela 803 is a cheap representative synthetic santalum essential oil that has therapeutic effects on neurodegenerative diseases. With development of nanotechnology, many types of nanomaterials loaded with fragrances could regulate release rate of aroma. However, most of them rely on destruction of interaction between fragrances and nanocarriers. These release processes are irreversible and un-sustained. In this study, light-activated mesoporous silica nanocolumns loaded with sandela 803 were designed, prepared and applied to wallpaper. The azobenzene derivatives modified with pore wall served as gatekeepers in the dark, and prevented guest molecules from escaping. By contrast, the azobenzene derivatives acted as brooms for impelling the sandela 803 from the mesoporous in the light. The structures and performances of light-activated mesoporous silica nanocolumns were quite stable during the release process. The release of sandela 803 was thus sustained and controlled. This kind of nano-fragrance with abilities of sustained and controlled release is expected to be used in the treatment of neurodegenerative diseases.
机译：Sandela 803是一种廉价的代表性合成桑坦卢姆精油，对神经变性疾病具有治疗作用。随着纳米技术的发展，载有香料的许多类型的纳米材料可以调节香气的释放速率。然而，大多数依赖于销毁香料和纳米载体之间的相互作用。这些释放过程是不可逆转的和不持续的。在本研究中，设计了用桑德拉803装载，制备并施加到壁纸的光激活的介孔二氧化硅纳米柱。用孔隙壁修饰的偶氮苯衍生物作为黑暗中的守门人，并防止客人分子逃逸。相比之下，偶氮苯衍生物作为扫帚，用于将Sandela 803从光线中的介孔中推动。在释放过程中，光活化的中孔二氧化硅纳米柱的结构和性能非常稳定。因此，Sandela 803的释放是持续和控制的。这种具有持续和控制释放能力的纳米香料预计将用于治疗神经变性疾病。

著录项

  • 来源
  • 作者

    Zhang Tianlu; Li Jian; Zhang Mengying; Lu Zhiguo; Wang Zhen; Shen Jie; Hu Jing; Niu Yunwei; Xiao Zuobing; Chen Lei; Mansmann Ulrich R.; Zhang Xin;

  • 作者单位

    Chinese Acad Sci Inst Proc Engn State Key Lab Biochem Engn Beijing 100190 Peoples R China;

    Ludwig Maximilians Univ Munchen Inst Med Informat Biometry &

    Epidemiol D-81377 Munich Germany;

    Ludwig Maximilians Univ Munchen Inst Med Informat Biometry &

    Epidemiol D-81377 Munich Germany;

    Chinese Acad Sci Inst Proc Engn State Key Lab Biochem Engn Beijing 100190 Peoples R China;

    Chinese Acad Sci Inst Proc Engn State Key Lab Biochem Engn Beijing 100190 Peoples R China;

    Chinese Acad Sci Inst Proc Engn State Key Lab Biochem Engn Beijing 100190 Peoples R China;

    Shanghai Res Inst Fragrance &

    Flavor Ind Shanghai 200232 Peoples R China;

    Shanghai Res Inst Fragrance &

    Flavor Ind Shanghai 200232 Peoples R China;

    Shanghai Res Inst Fragrance &

    Flavor Ind Shanghai 200232 Peoples R China;

    Navy Gen Hosp People Liberat Army Dept Obstet &

    Gynecol Beijing 100048 Peoples R China;

    Ludwig Maximilians Univ Munchen Inst Med Informat Biometry &

    Epidemiol D-81377 Munich Germany;

    Chinese Acad Sci Inst Proc Engn State Key Lab Biochem Engn Beijing 100190 Peoples R China;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 计量学;
  • 关键词

    Mesoporous Silica Nanocolumns; Fragrance; Light-Activated Release; Wallpaper; Azobenzene Derivatives;

    机译：中孔二氧化硅纳米柱;香味;光激活释放;壁纸;偶氮苯衍生物;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号