Challenging and refining treatment paradigms

Ball Mark W.; Srinivasan Ramaprasad

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Challenging and refining treatment paradigms

机译：挑战和精炼治疗范式

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Treatment paradigms for advanced renal cell carcinoma (RCC) continue to be challenged and refined. Recent studies in metastatic RCC have demonstrated the efficacy of first-line cabozantinib and the safety and efficacy of dual checkpoint blockade; in the adjuvant setting, pazopanib failed to improve progression-free survival in high-risk localized RCC compared with placebo.

机译：治疗肾细胞癌（RCC）的治疗范式继续受到挑战和精制。最近的转移性RCC的研究表明，一线Cabozantibib的疗效以及双重检查点封闭的安全性和有效性; 在佐剂设置中，Pazopanib与安慰剂相比，Pazopanib未能改善高风险局部RCC的无进展生存期。

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《Nature reviews. Urology》 |2018年第2期|共2页
作者
Ball Mark W.; Srinivasan Ramaprasad;
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NCI Urol Oncol Branch Ctr Canc Res NIH 10 Ctr Dr CRC2-5950 Bethesda MD 20892 USA;

NCI Urol Oncol Branch Ctr Canc Res NIH 10 Ctr Dr CRC2-5950 Bethesda MD 20892 USA;

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正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
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1. Challenging and refining treatment paradigms [J] . Ball Mark W., Srinivasan Ramaprasad Nature reviews. Urology . 2018,第2期

机译：挑战和精炼治疗范式
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Challenging and refining treatment paradigms

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