Revisiting 5 alpha-reductase inhibitors and the risk of prostate cancer

Chau Cindy H.; Figg William D.

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Revisiting 5 alpha-reductase inhibitors and the risk of prostate cancer

机译：重新发现5α-还原酶抑制剂和前列腺癌的风险

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The role of 5 alpha-reductase inhibitors (5-ARI) in prostate cancer chemoprevention remains a controversy, as cancer prevention trials with 5-ARIs have shown a decreased incidence of low-grade prostate cancer but a potential increased risk in high-grade disease. Recent studies have shed light on the long-term safety of 5-ARIs in terms of influencing prostate cancer risk.

机译：5α-还原酶抑制剂（5-ARI）在前列腺癌化学普通中的作用仍然是一种争议，因为5- aris的癌症预防试验显示出低级前列腺癌的发生率降低，但高级病的风险增加。在影响前列腺癌风险方面，最近的研究阐明了5-ARIS的长期安全性。

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《Nature reviews. Urology》 |2018年第7期|共3页
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Chau Cindy H.; Figg William D.;
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NCI Genitourinary Malignancies Branch Ctr Canc Res NIH Bethesda MD 20892 USA;

NCI Genitourinary Malignancies Branch Ctr Canc Res NIH Bethesda MD 20892 USA;

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正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
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1. Revisiting 5 alpha-reductase inhibitors and the risk of prostate cancer [J] . Chau Cindy H., Figg William D. Nature reviews. Urology . 2018,第7期

机译：重新发现5α-还原酶抑制剂和前列腺癌的风险
2. Use of 5 alpha-reductase inhibitors for benign prostate hypertrophy and risk of high-grade prostate cancer: a French population-based study [J] . Scailteux L. M., Balusson F., Rioux-Leclerc N., Fundamental & clinical pharmacology. . 2018,第S1期

机译：使用5种α-还原酶抑制剂进行良性前列腺肥大和高年级前列腺癌的风险：法国人口的研究
3. Active Surveillance of Very-low-risk Prostate Cancer in the Setting of Active Treatment of Benign Prostatic Hyperplasia With 5 alpha-reductase Inhibitors [J] . Peter Q. Shelton, Aliie N. Ivanowicz, Carolyn M. Wakeman, Urology . 2013,第5期

机译：积极监测非常低风险的前列腺癌，在积极治疗良性前列腺增生症的情况下，采用5种α-还原酶抑制剂
4. Prostate Cancer Prevention with 5 Alpha-Reductase Inhibitors [C] . D.J. Parekh International Conference on Clinical Cancer Prevention . 2011

机译：预防5α-还原酶抑制剂前列腺癌预防
5. Diet and prostate cancer: Investigating the relationship between risk of prostate cancer and serum concentrations of individual carotenoids, selenium, and alpha-tocopherol in United States Black and White men. [D] . Vogt, Tara Michelle. 2001

机译：饮食和前列腺癌：研究美国黑人和白人中前列腺癌风险与个体类胡萝卜素，硒和α-生育酚的血清浓度之间的关系。
6. Role of 5 alpha-reductase inhibitors in the management of prostate cancer [O] . Steven J Hudak, Javier Hernandez, Ian M Thompson 2006

机译：5种α-还原酶抑制剂在前列腺癌管理中的作用
7. Use of 5 alpha-reductase inhibitors for lower urinary tract symptoms and risk of prostate cancer in Swedish men : nationwide, population based case-control study [O] . Robinson, David, Garmo, Hans, Bill-Axelson, Anna, 2013

机译：在瑞典男性中使用5种α-还原酶抑制剂治疗下尿路症状和前列腺癌的风险：全国性，基于人群的病例对照研究

Revisiting 5 alpha-reductase inhibitors and the risk of prostate cancer

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