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首页> 外文期刊>Neurourology and urodynamics. >Transcutaneous posterior tibial nerve electrostimulation with low dose trospium chloride: Could it be used as a second line treatment of overactive bladder in females
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Transcutaneous posterior tibial nerve electrostimulation with low dose trospium chloride: Could it be used as a second line treatment of overactive bladder in females

机译：低剂量氯化钙的经皮后胫骨神经电刺激：它可以用作女性过度活性膀胱的第二线处理

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Aim To evaluate the effect of adding low dose trospium chloride with transcutaneous posterior tibial nerve stimulation (TPTNS) in the treatment of overactive bladder (OAB) in females after failure of behavioral therapy. Methods We randomized 30 women with OAB, in two groups: G I received 30?min TPTNS, three times a week; GII received TPTNS plus 20?mg trospium chloride daily. OAB Symptom Score questionnaire (OABSS), Incontinence Impact Questionnaire‐short form 7 (IIQ‐7), 3 day voiding diary and urodynamics at weeks 0 and 8 were evaluated. Results The groups were similar before treatment. Eight weeks after treatment, the mean OABSS decreased significantly to 8.53?±?1.30 for group II vs 10.0?±?2.0 for GI ( P ??0.024). The mean IIQ‐7 score decreased significantly to 51.86?±?17.26 in group I vs 31.99?±?9.26 in group II ( P ??0.001). Before treatment, 11 (73.3%) and 4 (26.7%) patients in each group had moderate and poor quality of life (QoL), respectively. After treatment, 6 (40%) and 14 (93.3%) had good QoL, 7 (46.7%) and 1 (6.7%) had moderate QoL in GI and GII, respectively. Two (13.3%) patients in GI had poor QoL. The mean frequency was reduced to 8.60?±?0.83 vs 10.60?±?2.32 for GII and GI respectively ( P ?=?0.006). The cystometric capacity increased from 263.40?±?50.45 to 377.80?±?112.92?mL ( P ?=?0.001) for GII vs 250.13?±?56.24 to 296.40?±?99.0?mL ( P ?=?0.026) for GI. Conclusion TPTNS combined with low dose trospium chloride proved to be more effective than TPTNS alone in the treatment of OAB in females.
机译：目的在于在行为治疗失败后，评估用经皮下后胫骨神经刺激（TPTN）加入低剂量氯化物与经皮后胫骨神经刺激（TPTN）的效果。方法我们将30名妇女随机组合，两组：G我收到30？最小TPTN，每周三次; GII每天收到TPTN加20毫克氯化钡。 OAB症状评分问卷调查问卷（OABS），失禁影响问卷 - 短型7（IIQ-7），评估3天的排尿日记和狼动力学。结果群体在治疗前相似。治疗后八周，平均OAbs显着降低至8.53°α≤1.3.30.0对10.0〜0.0的±2.0（p≤0.024）。平均IIQ-7分数明显减少至51.86°（±17.26），在II族中的31.99〜±9.26℃（p？＆ 0.001）。在治疗前，每组的11例（73.3％）和4名（26.7％）患者分别具有中等和差的生命质量（QOL）。处理后，6（40％）和14（93.3％）具有良好的QoL，7（46.7％）和1（6.7％）分别在GI和GII中具有中等的QoL。两种（13.3％）GI患者有贫穷的QOL。平均频率降至8.60？±0.83 Vs 10.60？±2.32分别用于GII和Gi（p？= 0.006）。膀胱测量容量从263.40增加到±50.45至377.80？ 。结论TPTN与低剂量氯化氯化物相结合，被证明比单独的TPTNS在雌性oab中的TPTNS更有效。

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