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Anorectal physiology in health: A randomized trial to determine the optimum catheter for the balloon expulsion test

机译:健康中的肛肠生理学:一种随机试验,以确定气球驱逐测试的最佳导管

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Abstract Background Anorectal manometry (ARM) and balloon expulsion test (BET) are pivotal in investigation of anorectal disorders. There is controversy, however, about normal values and optimum methodology for performing these tests. Our aims were to compare BET using three different balloons and to establish normal values for ARM and BET in health. Methods Forty‐four female healthy subjects (mean age 56?±?12?years) underwent ARM, followed by BET which was performed in a private toilet using three different catheters (party balloon, Foley catheter and a commercially available catheter) in a single‐blinded randomized order. Outcome measures were time to balloon expulsion and comprehensive measures of anal sphincter function, the push maneuver and rectal sensation. Key Results The Foley catheter took longer to expel compared to both party and commercial balloons (both pairwise P ??0.001) with a wider distribution of results ( P ??0.001). Ten of 40 healthy subjects could not expel the Foley catheter within 120?seconds. On ARM, older age was associated with lower resting anal sphincter pressure ( ρ? =??0.3, P ?=?0.05) and lower anal squeeze pressure ( ρ ?=??0.3, P ?=?0.05). Having at least one vaginal delivery (compared to none) was associated with lower anal squeeze pressures ( P ?=?0.03) and a smaller difference between cough and squeeze pressures ( P ?=?0.03). Conclusions & Inferences A commercial balloon exhibited superior results in vivo compared to the Foley catheter without the concerns of latex allergy and quality control present with the use of a party balloon. Normal values for high‐resolution water‐perfused manometry have been established and an effect seen for age and parity.
机译:摘要背景肛周测压(ARM)和气球驱逐试验(BET)是痛苦的肛肠疾病的研究。然而,关于正常值和用于执行这些测试的最佳方法,存在争议。我们的目标是使用三种不同的气球进行比较,并建立正常的手臂和健康赌注。方法四十四个女性健康受试者(平均56岁?丛生的随机顺序。结果措施是时间来气球驱逐和肛门括约肌综合措施,推动机动和直肠轰动。关键结果Foley导管与一方和商业气球(两者P≤0.001)相比,将更长时间排出(两者P 1 0.001),其结果较宽分布(P≤≤0.001)。 40个健康受试者中的十分之一无法在120℃以内排出Foley导管。在臂上,年龄较大的年龄与较低的肛门括约肌压力有关(ρ?= ?? 0.3,p?= 0.05)和较低的肛门挤压压力(ρ?= ?? 0.3,p?= 0.05)。至少有一个阴道递送(与无)与较低的肛门挤压压力(P?= 0.03)相关,咳嗽和挤压压力之间的较小差异(p?= 0.03)。结论&与Foley导管相比,推论商业气球在Vivo中表现出优越的结果,而不是使用派对气球的乳胶过热和质量控制的担忧。已经建立了高分辨率水灌注测控的正常值,并且为年龄和平价显示的效果。

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