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首页> 外文期刊>Neurogastroenterology and motility >24‐hour monitoring of transient lower esophageal sphincter relaxation events by long‐term high‐resolution impedance manometry in normal volunteers: The “mirror phenomenon”
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24‐hour monitoring of transient lower esophageal sphincter relaxation events by long‐term high‐resolution impedance manometry in normal volunteers: The “mirror phenomenon”

机译：在正常志愿者中长期高分辨率阻抗测控进行24小时监测瞬态较低的食道括约肌放松事件：“镜子现象”

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Abstract Background The aim of this study was to investigate the frequency and circadian changes in transient lower esophageal sphincter relaxations (TLESRs) in normal volunteers using 24‐hour high‐resolution impedance manometry (HRIM). Methods Fifteen volunteers underwent HRIM. TLESRs were recorded during the mealtime, 2‐hour postprandial, daytime, and supine periods. The catheter was firmly secured to the nose, and subjects went home, ate normal meals, and continued routine daily activities. Key Results Successful recordings were obtained in 11 volunteers. Overall, 1083 TLESRs were documented; the average occurrence was 4.2/h, and the duration was 21.0?±?5.2?seconds. The majority of the TLESRs occurred during the 2‐hour postprandial (42.7%) and daytime (31.5%) periods, while 10.2% and 15.6% occurred during the mealtime and supine periods, respectively. Eight hundred and eighty‐six (81.8%) TLESRs were associated with reflux. Overall, 25.5% of TLESRs were preceded by partial secondary peristalsis (PSP), while 74.5% were preceded by nothing. Terminating events included primary peristalsis (PP; 40.3%), PSP (42.8%), full secondary peristalsis (FSP; 8.2%), or nothing (8.7%). Both preceding and terminating events periodically changed throughout the four periods. One hundred and twelve (10.3%) TLESRs with both preceding and terminating events of PSP, presenting as a “mirror phenomenon,” were documented. The majority of these TLESRs occurred during the supine (70.5%). Conclusions & Inferences Transient lower esophageal sphincter relaxations are common physiological motor events in normal volunteers; these events have certain circadian rhythms, as do the events that precede and terminate TLESR events. A special “mirror phenomenon” is observed when both the preceding and terminating events are PSP.
机译：摘要背景本研究的目的是使用24小时高分辨率阻抗测压（HRIM）来研究常规志愿者在正常志愿者中瞬时较低的食管括约肌松弛（TLESR）的频率和昼夜昼夜循环弛豫（TLESRS）的变化。方法十五件志愿者接受了HRIM。在餐饮时间，2小时餐后，白天和仰卧期间记录了TLESRS。导管牢固地固定在鼻子上，受试者回家，吃正常的饭菜，并继续进行日常的日常活动。关键结果在11名志愿者中获得了成功录音。总体而言，记录了1083个TLESRS;平均出现为4.2 / h，持续时间为21.0？±5.2？秒。大多数TLESR在2小时后的餐后（42.7％）和白天（31.5％）期间发生，而在膳食时间和仰卧期间发生10.2％和15.6％。八百八十六（81.8％）TLESRS与回流有关。总体而言，25.5％的TLESRS之前是部分次级蠕动（PSP），而74.5％则是没有任何内容。终止事件包括原发性蠕动（PP; 40.3％），PSP（42.8％），全次级蠕动（FSP; 8.2％），或者没有（8.7％）。在整个四个时期定期更改之前和终止事件。记录了一百十二（10.3％）的PSP事件的TLESRS，作为“镜像现象”，被记录为“镜面现象”。这些TLESR的大多数发生在仰卧期间（70.5％）。结论＆amp;推论短暂性较低的食管括约肌放松是普通志愿者的常见生理运动事件;这些事件具有某些昼夜节律，如前面和终止TLESR事件的事件一样。当前面的先前和终止事件都是PSP时，观察到特殊的“镜面现象”。

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