Sodium Is Detected by the OVLT to Regulate Sympathetic Tone

Guyenet Patrice G.

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Sodium Is Detected by the OVLT to Regulate Sympathetic Tone

机译：通过OVLT检测钠以调节交感神经

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Hypernatremia is known to elicit a rise in sympathetic tone and blood pressure. In this issue of Neuron, Nomura et al. (2018) now show that this is mediated via the organum vasculosum laminae terminalis (OVLT). Na+ activates OVLT neurons via a paracrine mechanism involving sodium channel Na-x expressed by astrocytes and the ependyma.

机译：众所周知，高肝脏血症会引起同情性的血压和血压的上升。在这个神经元问题中，Nomura等人。（2018）现在表明，这通过器官血管薄层末端（OVLT）介导。 Na +通过涉及星形胶质细胞和外延表达的钠通道Na-X的梯碱机制来激活OVLT神经元。

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《Neuron》 |2019年第1期|共3页
作者
Guyenet Patrice G.;
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Univ Virginia Dept Pharmacol Charlottesville VA 22908 USA;

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正文语种 eng
中图分类神经病学;
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1. Sodium Is Detected by the OVLT to Regulate Sympathetic Tone [J] . Guyenet Patrice G. Neuron . 2019,第1期

机译：通过OVLT检测钠以调节交感神经
2. A capillary hemostasis mechanism regulated by sympathetic tone and activity via factor VIII or von Willebrand's factor may function as a capillary gate variations in systemic vascular resistance. [J] . Coleman LS Medical hypotheses . 2006,第4期

机译：毛细血管的止血机制受交感神经张力和经由VIII因子或von Willebrand's因子的调节，可作为全身血管阻力中毛细血管门的变化。
3. Medullary and supramedullary mechanisms regulating sympathetic vasomotor tone. [J] . Dampney RA, Horiuchi J, Tagawa T, Acta physiologica Scandinavica . 2003,第3期

机译：调节交感性血管舒缩张力的髓和上髓机制。
4. Autonomic tone is impaired by prolonged bedrest and sympathetic tone before bedrest predicts tolerance to tilt after bedrest [C] . X. Xiao, R. Mukkamala, N. Sheynberg, Joint Engineering in Medicine and Biology Society-Biomedical Engineering Society Conference . 2002

机译：在床上卧床之前，通过长时间的卧床和交感神经音调损害自主神经音调预测卧床后倾斜的耐受性
5. Exercise training reduces ventricular arrhythmias through restoring calcium handling and sympathetic tone in myocardial infarction mice [D] . 秦如潔 2019

机译：运动训练可通过恢复心肌梗死小鼠的钙离子处理和交感神经张力来减少室性心律失常
6. Sympathetic tone and relation between sodium intake and blood pressure in the general population. [O] . J. Staessen, C. J. Bulpitt, L. Thijs, 1989

机译：普通人群的交感神经张力以及钠摄入量与血压之间的关系。
7. Sympathetic tone and relation between sodium intake and blood pressure in the general population. [O] . Staessen, J., Bulpitt, C. J., Thijs, L., 1989

机译：普通人群的交感神经张力以及钠摄入量与血压之间的关系。

Sodium Is Detected by the OVLT to Regulate Sympathetic Tone

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