Hidden Figures: A Non-translated RNA Regulates Axonal Neurotrophin Signaling

Panayotis Nicolas; Fainzilber Mike

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Hidden Figures: A Non-translated RNA Regulates Axonal Neurotrophin Signaling

机译：隐藏的数字：非翻译的RNA调节轴突神经营养蛋白信号传导

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In this issue of Neuron, Crerar et al. (2019) found Tp53inp2 as a highly expressed RNA in sympathetic neuron axons. Strikingly, its long 3 0 UTR ensures that Tp53inp2 is not translated in axons, and the untranslated RNA affects neuronal growth by interacting with neurotrophin receptors.

机译：在这个神经元，Crerar等人的问题中。（2019）发现TP53InP2作为同情神经元轴突中高表达的RNA。引人注目的是，它的长3 0 UTR确保TP53InP2在轴突中未翻译，并且未转换的RNA通过与神经营养素受体相互作用来影响神经元生长。

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《Neuron》 |2019年第3期|共3页
作者
Panayotis Nicolas; Fainzilber Mike;
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作者单位

Weizmann Inst Sci Dept Biomol Sci IL-7610001 Rehovot Israel;

Weizmann Inst Sci Dept Biomol Sci IL-7610001 Rehovot Israel;

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正文语种 eng
中图分类神经病学;
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1. Hidden Figures: A Non-translated RNA Regulates Axonal Neurotrophin Signaling [J] . Panayotis Nicolas, Fainzilber Mike Neuron . 2019,第3期

机译：隐藏的数字：非翻译的RNA调节轴突神经营养蛋白信号传导
2. Signalling organelle for retrograde axonal transport of internalized neurotrophins from the nerve terminal. [J] . Sandow SL, Heydon K, Weible MW-2nd, Immunology and Cell Biology . 2000,第4期

机译：信号细胞器，用于从神经末梢逆行内化神经营养蛋白的轴突运输。
3. MicroRNA‐141 binds to the nerve growth factor receptor associated protein 1 gene and restores the erectile function of diabetic rats through down‐regulating the nerve growth factor/neurotrophin receptor p75 (NGF/p75NTR) signaling [J] . Wen Yan, Liu Guohui, Jia Linpei, Journal of cellular biochemistry. . 2019,第5期

机译：microRNA-141与神经生长因子受体相关蛋白1基因结合，并通过下调神经生长因子/神经营养素受体P75（NGF / P75TR）信号传导来恢复糖尿病大鼠的勃起功能
4. Non-Catalytic TRK B Receptors Are Expressed In Developing Non-Neuronal Tissues In Patterns That Indicate The Receptor Regulates Target-Derived Neurotrophin Concentrations [C] . Wheeler, E.F., Gong, . 1998

机译：非催化性TRK B受体以指示受体调节靶标衍生的神经营养蛋白浓度的模式表达于发育的非神经元组织中。
5. Early effects of organophosphate compounds on in vitro intracellular signaling and levels of active neurotrophin receptors, and on in vivo neurotrophin concentrations [D] . Pomeroy-Black, Melinda Jane 2005

机译：有机磷酸盐化合物对体外细胞内信号传导和活性神经营养蛋白受体水平以及体内神经营养蛋白浓度的早期影响
6. PRC2 regulates RNA polymerase III transcribed non-translated RNA gene transcription through EZH2 and SUZ12 interaction with TFIIIC complex [O] . Chang Liu, Shuai Li, Xiaoyan Dai, 2015

机译：PRC2通过EZH2和SUZ12与TFIIIC复合体的相互作用调节RNA聚合酶III转录的非翻译RNA基因转录
7. Hidden Figures: A Non-translated RNA Regulates Axonal Neurotrophin Signaling [O] . Nicolas Panayotis, Mike Fainzilber 2019

机译：隐藏的数字：非翻译的RNA调节轴突神经营养蛋白信号传导
8. Hidden Figures are Ever Present [R] . Mens, L. H. M. , Leeuwenberg, E. L. J. 1983

机译：隐藏的数字永远存在

Hidden Figures: A Non-translated RNA Regulates Axonal Neurotrophin Signaling

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