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Profiles of Cognitive Impairments in an Older Age Community Sample: A Latent Class Analysis

机译：年龄较大的社区样本中的认知障碍概况：潜在课程分析

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Objective: Person-centered studies that could describe the different patterns of cognitive impairments among older people are lacking. To this end, the current study utilized a person-centered approach to examine the different profiles of cognitive impairment in an older age Chinese community sample. Additionally, the current study also examined whether functional impairments differ across the different profiles. Method: A total of 220 older people (M-age = 70.9 years) who were assessed to have an objective impairment in any of 7 domains (immediate memory, delayed memory, attention, inhibition, verbal fluency, working memory, and processing speed) were entered in a latent class analysis. Subsequently, functional impairment (both self-reported and clinician-rated) between the different profiles of cognitive impairments that emerged from the analyses were compared. Results: A 4-class solution was chosen based on fit statistics and interpretability. Three profiles were characterized by impairments in cognitive rigidity, memory, and other executive functions, and the 4th with impairments in both executive functions and memory. Furthermore, relative to the non-memory-impaired groups, the memory-impaired groups were significantly more likely to report a higher level of clinician-rated functional impairments even though these groups did not differ significantly in self-reported functional impairments. Conclusions: The observed cognitive impairments in the current sample can be classified into 4 distinct profiles along the lines of memory and/or executive functions impairment. The memory-impaired groups were significantly impaired relative to the non-memory-impaired groups, at least in terms of clinician-rated functional outcomes. These findings present some important implications.
机译：目的：以人为本的研究，可以描述老年人之间的认知障碍模式的不同研究。为此，目前的研究利用了一个以人为本的方法来检查旧时代中国社区样本中的认知障碍的不同概况。此外，目前的研究还检查了功能性损伤是否在不同的轮廓上不同。方法：共有220名更老的人（M-ysge = 70.9岁），他们被评估为7个域中的任何一个客观损害（立即内存，延迟记忆，注意，抑制，口头流畅，工作记忆和处理速度）在潜在的阶级分析中进入。随后，比较了从分析中出现的认知障碍的不同概况之间的功能损伤（自我报告和临床医生额定）。结果：基于拟合统计和解释性选择4级解决方案。通过认知刚性，记忆和其他行政职能的损害，以及在执行职能和记忆中的障碍中的损伤是特征。此外，相对于非记忆受损的基团，即使这些群体在自我报告的功能障碍中没有显着差异，内存受损的群体也显着提高更高水平的临床医生额定功能障碍。结论：目前样品中观察到的认知障碍可以沿着记忆线和/或执行职能损伤分为4个不同的曲线。至少在临床医生的功能结果方面，内存受损的基团相对于非记忆受损的群体显着受损。这些发现存在一些重要的含义。

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