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首页> 外文期刊>Neuroscience Research: The Official Journal of the Japan Neuroscience Society >Temporal patterning of neurogenesis and neural wiring in the fly visual system
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Temporal patterning of neurogenesis and neural wiring in the fly visual system

机译:苍蝇视觉系统中神经发生和神经布线的颞剖视图

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During neural development, a wide variety of neurons are produced in a highly coordinated manner and form complex and highly coordinated neural circuits. Temporal patterning of neuron type specification plays very important roles in orchestrating the production and wiring of neurons. The fly visual system, which is composed of the retina and the optic lobe of the brain, is an outstanding model system to study temporal patterning and wiring of the nervous system. All of the components of the fly visual system are topographically connected, and each ommatidial unit in the retina corresponds to a columnar unit in the optic lobe. In the retina, the wave of differentiation follows the morphogenetic furrow, which progresses in a posterior-to-anterior direction. At the same time, differentiation of the optic lobe also accompanies the wave of differentiation or temporally coordinated neurogenesis. Thus, temporal patterning plays important roles in establishing topographic connections throughout the fly visual system. In this article, we review how neuronal differentiation and connectivity are orchestrated in the fly visual system by temporal patterning mechanisms. (C) 2018 Elsevier B.V. and Japan Neuroscience Society. All rights reserved.
机译:在神经发育期间,各种神经元以高度协调的方式生产,形成复杂和高度协调的神经电路。神经元类型规范的颞型图案化在协调神经元的生产和接线方面起着非常重要的作用。苍蝇视觉系统,由视​​网膜和大脑的视神经组成,是一个优秀的模型系统,用于研究神经系统的时间图案化和布线。翼视觉系统的所有组件都是拓扑连接的,并且视网膜中的每个OMMativial单元对应于视光瓣中的柱状单元。在视网膜中,差异化的浪潮遵循形态发生的沟槽,其在后向前方方向上进行。同时,视神经叶的分化还伴随着分化的潮或时间协调的神经发生。因此,时间图案化在整个飞行视觉系统中建立地形连接起着重要作用。在本文中,我们审查了神经元分化和连接是如何通过颞型图案化机制在飞行视觉系统中进行策划的。 (c)2018年Elsevier B.V.和日本神经科学社会。版权所有。

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